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Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
Table 2Targets from Ricerca profiling that showed > 50% inhibition
| Cat # | Assay Name | Species | Conc. | % Inh. |
|---|---|---|---|---|
| 214600 | Calcium Channel L-Type, Digydropyridine | Rat | 10μM | 79 |
| 224010 | Edothelin ETA | Hum | 10μM | 66 |
| 251600 | Melatonin MT1 | Hum | 10μM | 64 |
| 260210 | Opiate k(OP2, KOP) | Hum | 10μM | 67 |
- Review ML365: Development of Bis-Amides as Selective Inhibitors of the KCNK3/TASK1 Two Pore Potassium Channel.[Probe Reports from the NIH Mol...]Review ML365: Development of Bis-Amides as Selective Inhibitors of the KCNK3/TASK1 Two Pore Potassium Channel.Zou B, Flaherty DP, Simpson DS, Maki BE, Miller MR, Shi J, Wu M, McManus OB, Golden JE, Aubé J, et al. Probe Reports from the NIH Molecular Libraries Program. 2010
- Review Identification of a novel, small molecule inhibitor of KCNQ2 channels.[Probe Reports from the NIH Mol...]Review Identification of a novel, small molecule inhibitor of KCNQ2 channels.Yu H, Xu K, Zou B, Wu M, McManus OB, Le Engers J, Cheung YY, Salovich JM, Hopkins CR, Lindsley CW, et al. Probe Reports from the NIH Molecular Libraries Program. 2010
- Review Identification of a novel, small molecule activator of KCNQ1 channels.[Probe Reports from the NIH Mol...]Review Identification of a novel, small molecule activator of KCNQ1 channels.Yu H, Lin Z, Xu K, Huang X, Long S, Wu M, McManus OB, Le Engers J, Mattmann ME, Engers DW, et al. Probe Reports from the NIH Molecular Libraries Program. 2010
- Terbinafine is a novel and selective activator of the two-pore domain potassium channel TASK3.[Biochem Biophys Res Commun. 2017]Terbinafine is a novel and selective activator of the two-pore domain potassium channel TASK3.Wright PD, Veale EL, McCoull D, Tickle DC, Large JM, Ococks E, Gothard G, Kettleborough C, Mathie A, Jerman J. Biochem Biophys Res Commun. 2017 Nov 4; 493(1):444-450. Epub 2017 Sep 5.
- A pharmacologically validated, high-capacity, functional thallium flux assay for the human Ether-à-go-go related gene potassium channel.[Assay Drug Dev Technol. 2010]A pharmacologically validated, high-capacity, functional thallium flux assay for the human Ether-à-go-go related gene potassium channel.Schmalhofer WA, Swensen AM, Thomas BS, Felix JP, Haedo RJ, Solly K, Kiss L, Kaczorowski GJ, Garcia ML. Assay Drug Dev Technol. 2010 Dec; 8(6):714-26.
- Table 2, Targets from Ricerca profiling that showed > 50% inhibition - Probe Rep...Table 2, Targets from Ricerca profiling that showed > 50% inhibition - Probe Reports from the NIH Molecular Libraries Program
- PABPC1L poly(A) binding protein cytoplasmic 1 like [Homo sapiens]PABPC1L poly(A) binding protein cytoplasmic 1 like [Homo sapiens]Gene ID:80336Gene
- Gene Links for GEO Profiles (Select 127408331) (1)Gene
- CCN5 cellular communication network factor 5 [Homo sapiens]CCN5 cellular communication network factor 5 [Homo sapiens]Gene ID:8839Gene
- Gene Links for GEO Profiles (Select 127408328) (1)Gene
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