Scheme D1Synthesis of the Amgen Compound 1 (control)
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- A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells.[ACS Med Chem Lett. 2012]A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells.Weïwer M, Spoonamore J, Wei J, Guichard B, Ross NT, Masson K, Silkworth W, Dandapani S, Palmer M, Scherer CA, et al. ACS Med Chem Lett. 2012 Dec 13; 3(12):1034-1038. Epub 2012 Oct 22.
- STK33 kinase activity is nonessential in KRAS-dependent cancer cells.[Cancer Res. 2011]STK33 kinase activity is nonessential in KRAS-dependent cancer cells.Babij C, Zhang Y, Kurzeja RJ, Munzli A, Shehabeldin A, Fernando M, Quon K, Kassner PD, Ruefli-Brasse AA, Watson VJ, et al. Cancer Res. 2011 Sep 1; 71(17):5818-26. Epub 2011 Jul 8.
- Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33.[J Exp Med. 2012]Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33.Azoitei N, Hoffmann CM, Ellegast JM, Ball CR, Obermayer K, Gößele U, Koch B, Faber K, Genze F, Schrader M, et al. J Exp Med. 2012 Apr 9; 209(4):697-711. Epub 2012 Mar 26.
- Review KRAS mutations in lung cancer.[Clin Lung Cancer. 2013]Review KRAS mutations in lung cancer.Karachaliou N, Mayo C, Costa C, Magrí I, Gimenez-Capitan A, Molina-Vila MA, Rosell R. Clin Lung Cancer. 2013 May; 14(3):205-14. Epub 2012 Nov 1.
- Review Gene methylation in gastric cancer.[Clin Chim Acta. 2013]Review Gene methylation in gastric cancer.Qu Y, Dang S, Hou P. Clin Chim Acta. 2013 Sep 23; 424:53-65. Epub 2013 May 10.
- Scheme D1, Synthesis of the Amgen Compound 1 (control) - Probe Reports from the ...Scheme D1, Synthesis of the Amgen Compound 1 (control) - Probe Reports from the NIH Molecular Libraries Program
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