8QIC: Structure-based identification of salicylic acid derivatives as malarial threonyl tRNA-synthetase inhibitors

PDB ID: 8QICDownload
MMDB ID: 245212
PDB Deposition Date: 2023/9/13
Updated in MMDB: 2024/04
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 8QIC: dimeric; determined by author and by software (PISA)
Molecular Components in 8QIC
Label Count Molecule
Proteins (2 molecules)
2
Threonine--trna Ligase
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
2-oxidanyl-5-[[4-(phenylmethyl)phenyl]sulfamoyl]benzoic acid2-oxidanyl-5-[[4-(phenylmethyl)phenyl]sulfamoyl]benzoic acid
2
4
GLYCEROLGLYCEROL
3
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303