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Conserved domains on  [gi|2096088362|ref|WP_223197981|]
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MULTISPECIES: isochorismate synthase MenF [Staphylococcus]

Protein Classification

isochor_syn family protein( domain architecture ID 10015682)

isochor_syn family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
isochor_syn TIGR00543
isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, ...
 89-432 9.86e-167

isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, different loci encode isochorismate synthases for the pathways of menaquinone biosynthesis and enterobactin biosynthesis (via salicilate) and fail to complement each other. Among isochorismate synthases, the N-terminal domain is poorly conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


:

Pssm-ID: 273127  Cd Length: 351  Bit Score: 472.62  E-value: 9.86e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362  89 LRVVGGFQFSSHKSDDeWREFGLNHFVLPEVLISTDNNGTFLTYTVKRESFTVEALNDLMDLFNNISDID----VDEQIG 164
Cdd:TIGR00543   1 PRLFGGFPFDPEEPAA-WEEFGEGYFVLPEVLVESDGGGTLLTCTIVAEPELNEADLLLYAKFAVSSGIRplraLPEQMT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 165 EITRNEDIYKDDWRQLVVEAIESINNE--EKIVLARRRLIKFDKDISIPYILKQAYSKEKNSYIFLLE-SQDSIFFSQTP 241
Cdd:TIGR00543  80 TLTTGEDPDKAAWRTAVEEALENIRQGplDKVVLARALTLKFADDIDPIAVLANLRQQYPNAYIFLLEpPQGGVFLGATP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 242 EQLIKVNNKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKPYITELHYDKTPKILKNDHLYH 321
Cdd:TIGR00543 160 ERLLSREKGELLTEALAGTAPRSADPEEDRKLGELLLKDDKNLREHRLVVEYIRRRLQPICTSLDVSETPELLKLANVQH 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 322 LYTEIKAPLKD-DSYISLIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKKAQA 400
Cdd:TIGR00543 240 LYTPISARLKDgDSLLDLLKQLHPTPAVGGLPREEALDFIREHEPFDRGLYAAPLGWLDGEGNGEFAVGIRSALVEDGQV 319

                         330       340       350
                  ....*....|....*....|....*....|..
gi 2096088362 401 TLFAGCGIVKDSDPDSELAETNLKFTPMMNAL 432
Cdd:TIGR00543 320 RLYAGAGIVADSDPESEWEETELKLQTMLRAL 351
 
Name Accession Description Interval E-value
isochor_syn TIGR00543
isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, ...
 89-432 9.86e-167

isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, different loci encode isochorismate synthases for the pathways of menaquinone biosynthesis and enterobactin biosynthesis (via salicilate) and fail to complement each other. Among isochorismate synthases, the N-terminal domain is poorly conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273127  Cd Length: 351  Bit Score: 472.62  E-value: 9.86e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362  89 LRVVGGFQFSSHKSDDeWREFGLNHFVLPEVLISTDNNGTFLTYTVKRESFTVEALNDLMDLFNNISDID----VDEQIG 164
Cdd:TIGR00543   1 PRLFGGFPFDPEEPAA-WEEFGEGYFVLPEVLVESDGGGTLLTCTIVAEPELNEADLLLYAKFAVSSGIRplraLPEQMT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 165 EITRNEDIYKDDWRQLVVEAIESINNE--EKIVLARRRLIKFDKDISIPYILKQAYSKEKNSYIFLLE-SQDSIFFSQTP 241
Cdd:TIGR00543  80 TLTTGEDPDKAAWRTAVEEALENIRQGplDKVVLARALTLKFADDIDPIAVLANLRQQYPNAYIFLLEpPQGGVFLGATP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 242 EQLIKVNNKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKPYITELHYDKTPKILKNDHLYH 321
Cdd:TIGR00543 160 ERLLSREKGELLTEALAGTAPRSADPEEDRKLGELLLKDDKNLREHRLVVEYIRRRLQPICTSLDVSETPELLKLANVQH 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 322 LYTEIKAPLKD-DSYISLIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKKAQA 400
Cdd:TIGR00543 240 LYTPISARLKDgDSLLDLLKQLHPTPAVGGLPREEALDFIREHEPFDRGLYAAPLGWLDGEGNGEFAVGIRSALVEDGQV 319

                         330       340       350
                  ....*....|....*....|....*....|..
gi 2096088362 401 TLFAGCGIVKDSDPDSELAETNLKFTPMMNAL 432
Cdd:TIGR00543 320 RLYAGAGIVADSDPESEWEETELKLQTMLRAL 351
MenF COG1169
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites ...
 34-435 2.54e-111

Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440783 [Multi-domain]  Cd Length: 353  Bit Score: 331.35  E-value: 2.54e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362  34 DRFYMRLNDNRTSYFGYKAIQLFKNNSKNKQSIFKD-WEKLkhnitFIHPQSEKHHLRVVGGFQFSSHKSDdewrefGLN 112
Cdd:COG1169     1 PRFYWASPDRGEGLAGLGEAARFEAPGPDRFAALAAaWQAL-----LADAALAGTGPRAFGGFAFDPDSPA------PAA 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 113 HFVLPEVLIStdnngtfltytvkresftvealndlmdlfnnisdidvdeqigeITRNEDIYKDDWRQLVVEAIESINNEE 192
Cdd:COG1169    70 RLVLPRLLLR-------------------------------------------RSRRGVPDPAEWREAVAQALEAIRAGE 106

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 193 --KIVLARRRLIKFDKDISIPYILKQAYSKEKNSYIFLLE-SQDSIFFSQTPEQLIKVNNKILSTKAVAGTIKRSQDEDE 269
Cdd:COG1169   107 ldKVVLARALDLTLDEPIDPRALLARLRRRNPDCYTFAVElGAGDGFVGASPERLVRRRGGQLTTEALAGTAPRGADPEE 186

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 270 DTKNVEAFLKDNKNLIEHRFVVDSILHDIKPYITELHYDKTPKILKNDHLYHLYTEIKAPLKDD-SYISLIDHLHPTPAL 348
Cdd:COG1169   187 DAALAAALLASEKDRREHALVVDSIREALAPLCSSLDVPEEPELLRLRNVQHLATPITGTLDPGvSALDLAAALHPTPAV 266

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 349 GGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKKAQATLFAGCGIVKDSDPDSELAETNLKFTPM 428
Cdd:COG1169   267 GGTPREAALALIRELEPFDRGWYAGPVGWVDADGDGEFAVAIRSALIDGNRARLFAGAGIVAGSDPEAEWAETEAKLRTM 346


                  ....*..
gi 2096088362 429 MNALGVD 435
Cdd:COG1169   347 LRALGLE 353
Chorismate_bind pfam00425
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ...
 175-424 6.45e-80

chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.


Pssm-ID: 425674 [Multi-domain]  Cd Length: 255  Bit Score: 247.47  E-value: 6.45e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 175 DDWRQLVVEAIESINNEE--KIVLARRRLIKFDKDISIPYILKQAYSKEKNSYIFLLESQDSIFFSQTPEQLIKVNNKIL 252
Cdd:pfam00425   1 EDYLAAVEKAKEAIRAGDlyKVVLSRRLTLPLAGDIDPLALYRRLRARNPAPYSFYFRTGDFTFLGASPERLLSVDGGRI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 253 STKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKPYI--TELHYDKTPKILKNDHLYHLYTEIKAPL 330
Cdd:pfam00425  81 ITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCvpGSVKVPELPEVERYGTVQHLVSTISGRL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 331 KDD-SYISLIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKKAQATLFAGCGIV 409
Cdd:pfam00425 161 KPGlSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRARLYAGAGIV 240

                         250
                  ....*....|....*
gi 2096088362 410 KDSDPDSELAETNLK 424
Cdd:pfam00425 241 ADSDPEAEWEETEAK 255
PRK07054 PRK07054
isochorismate synthase;
7-434 7.41e-69

isochorismate synthase;


Pssm-ID: 235920 [Multi-domain]  Cd Length: 475  Bit Score: 226.18  E-value: 7.41e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362   7 EWVSVEVKL-SQSLDPSTLFHLTDNEAGDRFYMRLNDNRTSYFGYK-AIQLFKNNSKNKQSIFKDWEKLKHNITFIHPQS 84
Cdd:PRK07054   24 RPVLAAASFpLRPLDPFDLFAAWDDGATPWCFWEAGDLPVALFGWGcALELNAHGDQRFARLEARWRALVADAVVAGPQP 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362  85 EkhhlRVVGGFQFSSHKSDDE-WREFGLNHFVLPEVLISTDNNGTFLTYTVkresfTVEALNDLMDLFNNI--------- 154
Cdd:PRK07054  104 P----RLVGGFRFDPRGPRSAhWQAFADASLTLAKLLVVREGEAYWAVCQH-----LVAAHDDPAALAGACcarierlar 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 155 ----SDIDVDEQIgeitRNEDIYKDDWRQLVVEAIESINNEE--KIVLARRRLIKFDKDISIPYILKQAYSKEKNSYIFL 228
Cdd:PRK07054  175 papaADDDAPRLL----RASALQAREWQHEVRRAVDAIRGGAfgKVVLARDVLQQYARPVAIGPLLRRLRLRDPHAHLFA 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 229 LESQDSIFFSQTPEQLIKVNNKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKPYITELHYD 308
Cdd:PRK07054  251 FRRGNACFLGATPERLVRVAAGDLHTHALAGTIARGADPAEDARLGAALMASAKDRLEHALVVDAIRAALAPLSRALDIP 330

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 309 KTPKILKNDHLYHLYTEIKAPLKDD-SYISLIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFI 387
Cdd:PRK07054  331 DQPSLHRLPRLQHLSTPIRATLAPDaTLLQVVAALHPTPAVGGHPRAAALDYIRAHEGFDRGWYAAPIGWLDAHGNGDFA 410

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 2096088362 388 VAIRSMLIKKAQATLFAGCGIVKDSDPDSELAETNLKFTPMMNALGV 434
Cdd:PRK07054  411 VALRSALITGGACRLFAGCGIVADSEPASEYRETCLKLSGMREALRA 457
 
Name Accession Description Interval E-value
isochor_syn TIGR00543
isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, ...
 89-432 9.86e-167

isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, different loci encode isochorismate synthases for the pathways of menaquinone biosynthesis and enterobactin biosynthesis (via salicilate) and fail to complement each other. Among isochorismate synthases, the N-terminal domain is poorly conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273127  Cd Length: 351  Bit Score: 472.62  E-value: 9.86e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362  89 LRVVGGFQFSSHKSDDeWREFGLNHFVLPEVLISTDNNGTFLTYTVKRESFTVEALNDLMDLFNNISDID----VDEQIG 164
Cdd:TIGR00543   1 PRLFGGFPFDPEEPAA-WEEFGEGYFVLPEVLVESDGGGTLLTCTIVAEPELNEADLLLYAKFAVSSGIRplraLPEQMT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 165 EITRNEDIYKDDWRQLVVEAIESINNE--EKIVLARRRLIKFDKDISIPYILKQAYSKEKNSYIFLLE-SQDSIFFSQTP 241
Cdd:TIGR00543  80 TLTTGEDPDKAAWRTAVEEALENIRQGplDKVVLARALTLKFADDIDPIAVLANLRQQYPNAYIFLLEpPQGGVFLGATP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 242 EQLIKVNNKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKPYITELHYDKTPKILKNDHLYH 321
Cdd:TIGR00543 160 ERLLSREKGELLTEALAGTAPRSADPEEDRKLGELLLKDDKNLREHRLVVEYIRRRLQPICTSLDVSETPELLKLANVQH 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 322 LYTEIKAPLKD-DSYISLIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKKAQA 400
Cdd:TIGR00543 240 LYTPISARLKDgDSLLDLLKQLHPTPAVGGLPREEALDFIREHEPFDRGLYAAPLGWLDGEGNGEFAVGIRSALVEDGQV 319

                         330       340       350
                  ....*....|....*....|....*....|..
gi 2096088362 401 TLFAGCGIVKDSDPDSELAETNLKFTPMMNAL 432
Cdd:TIGR00543 320 RLYAGAGIVADSDPESEWEETELKLQTMLRAL 351
MenF COG1169
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites ...
 34-435 2.54e-111

Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440783 [Multi-domain]  Cd Length: 353  Bit Score: 331.35  E-value: 2.54e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362  34 DRFYMRLNDNRTSYFGYKAIQLFKNNSKNKQSIFKD-WEKLkhnitFIHPQSEKHHLRVVGGFQFSSHKSDdewrefGLN 112
Cdd:COG1169     1 PRFYWASPDRGEGLAGLGEAARFEAPGPDRFAALAAaWQAL-----LADAALAGTGPRAFGGFAFDPDSPA------PAA 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 113 HFVLPEVLIStdnngtfltytvkresftvealndlmdlfnnisdidvdeqigeITRNEDIYKDDWRQLVVEAIESINNEE 192
Cdd:COG1169    70 RLVLPRLLLR-------------------------------------------RSRRGVPDPAEWREAVAQALEAIRAGE 106

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 193 --KIVLARRRLIKFDKDISIPYILKQAYSKEKNSYIFLLE-SQDSIFFSQTPEQLIKVNNKILSTKAVAGTIKRSQDEDE 269
Cdd:COG1169   107 ldKVVLARALDLTLDEPIDPRALLARLRRRNPDCYTFAVElGAGDGFVGASPERLVRRRGGQLTTEALAGTAPRGADPEE 186

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 270 DTKNVEAFLKDNKNLIEHRFVVDSILHDIKPYITELHYDKTPKILKNDHLYHLYTEIKAPLKDD-SYISLIDHLHPTPAL 348
Cdd:COG1169   187 DAALAAALLASEKDRREHALVVDSIREALAPLCSSLDVPEEPELLRLRNVQHLATPITGTLDPGvSALDLAAALHPTPAV 266

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 349 GGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKKAQATLFAGCGIVKDSDPDSELAETNLKFTPM 428
Cdd:COG1169   267 GGTPREAALALIRELEPFDRGWYAGPVGWVDADGDGEFAVAIRSALIDGNRARLFAGAGIVAGSDPEAEWAETEAKLRTM 346


                  ....*..
gi 2096088362 429 MNALGVD 435
Cdd:COG1169   347 LRALGLE 353
Chorismate_bind pfam00425
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ...
 175-424 6.45e-80

chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.


Pssm-ID: 425674 [Multi-domain]  Cd Length: 255  Bit Score: 247.47  E-value: 6.45e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 175 DDWRQLVVEAIESINNEE--KIVLARRRLIKFDKDISIPYILKQAYSKEKNSYIFLLESQDSIFFSQTPEQLIKVNNKIL 252
Cdd:pfam00425   1 EDYLAAVEKAKEAIRAGDlyKVVLSRRLTLPLAGDIDPLALYRRLRARNPAPYSFYFRTGDFTFLGASPERLLSVDGGRI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 253 STKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKPYI--TELHYDKTPKILKNDHLYHLYTEIKAPL 330
Cdd:pfam00425  81 ITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCvpGSVKVPELPEVERYGTVQHLVSTISGRL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 331 KDD-SYISLIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKKAQATLFAGCGIV 409
Cdd:pfam00425 161 KPGlSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRARLYAGAGIV 240

                         250
                  ....*....|....*
gi 2096088362 410 KDSDPDSELAETNLK 424
Cdd:pfam00425 241 ADSDPEAEWEETEAK 255
PRK07054 PRK07054
isochorismate synthase;
7-434 7.41e-69

isochorismate synthase;


Pssm-ID: 235920 [Multi-domain]  Cd Length: 475  Bit Score: 226.18  E-value: 7.41e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362   7 EWVSVEVKL-SQSLDPSTLFHLTDNEAGDRFYMRLNDNRTSYFGYK-AIQLFKNNSKNKQSIFKDWEKLKHNITFIHPQS 84
Cdd:PRK07054   24 RPVLAAASFpLRPLDPFDLFAAWDDGATPWCFWEAGDLPVALFGWGcALELNAHGDQRFARLEARWRALVADAVVAGPQP 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362  85 EkhhlRVVGGFQFSSHKSDDE-WREFGLNHFVLPEVLISTDNNGTFLTYTVkresfTVEALNDLMDLFNNI--------- 154
Cdd:PRK07054  104 P----RLVGGFRFDPRGPRSAhWQAFADASLTLAKLLVVREGEAYWAVCQH-----LVAAHDDPAALAGACcarierlar 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 155 ----SDIDVDEQIgeitRNEDIYKDDWRQLVVEAIESINNEE--KIVLARRRLIKFDKDISIPYILKQAYSKEKNSYIFL 228
Cdd:PRK07054  175 papaADDDAPRLL----RASALQAREWQHEVRRAVDAIRGGAfgKVVLARDVLQQYARPVAIGPLLRRLRLRDPHAHLFA 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 229 LESQDSIFFSQTPEQLIKVNNKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKPYITELHYD 308
Cdd:PRK07054  251 FRRGNACFLGATPERLVRVAAGDLHTHALAGTIARGADPAEDARLGAALMASAKDRLEHALVVDAIRAALAPLSRALDIP 330

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 309 KTPKILKNDHLYHLYTEIKAPLKDD-SYISLIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFI 387
Cdd:PRK07054  331 DQPSLHRLPRLQHLSTPIRATLAPDaTLLQVVAALHPTPAVGGHPRAAALDYIRAHEGFDRGWYAAPIGWLDAHGNGDFA 410

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 2096088362 388 VAIRSMLIKKAQATLFAGCGIVKDSDPDSELAETNLKFTPMMNALGV 434
Cdd:PRK07054  411 VALRSALITGGACRLFAGCGIVADSEPASEYRETCLKLSGMREALRA 457
PRK06923 PRK06923
isochorismate synthase DhbC; Validated
 192-439 3.45e-48

isochorismate synthase DhbC; Validated


Pssm-ID: 235886 [Multi-domain]  Cd Length: 399  Bit Score: 169.53  E-value: 3.45e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 192 EKIVLARRRLIKFDKDISIPYILKQAYSKEKNSYIF---LLESQDS---IFFSQTPEQLIKVNNKILSTKAVAGTIKRSQ 265
Cdd:PRK06923  141 KKIVLSRSLDVKSSEKIDKQKLLRELAEHNKHGYTFavnLPKDENEnskTLIGASPELLVSRHGMQVISNPLAGSRPRSD 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 266 DEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKPYITELHYDKTPKILKNDHLYHLYTEIKAPLKDDSYISL--IDHLH 343
Cdd:PRK06923  221 DPVEDKRRAEELLSSPKDLHEHAVVVEAVAAALRPYCHTLHVPEKPSVIHTEAMWHLSTEVKGELKDPNTSSLelAIALH 300

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 344 PTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKKAQATLFAGCGIVKDSDPDSELAETNL 423
Cdd:PRK06923  301 PTPAVCGTPTEEAREAIQQIEPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVEENTLRLYAGAGVVAESKPEDELAETSA 380

                         250
                  ....*....|....*....
gi 2096088362 424 KFTPMMNALGVD---MNGK 439
Cdd:PRK06923  381 KFQTMLKAMGLNdssLNEK 399
PLN02786 PLN02786
isochorismate synthase
 68-424 3.51e-38

isochorismate synthase


Pssm-ID: 178383 [Multi-domain]  Cd Length: 533  Bit Score: 145.31  E-value: 3.51e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362  68 KDWEKLKHnitFIhpqSEKHHL-RVVGGFQFSSH-KSDDEWREFGLNHFVLPEVLISTDNNGTFLTYTVKRE---SFTVE 142
Cdd:PLN02786  148 DDWRSIKR---FL---SSKSPLiRAYGAIRFDPNgKISVEWEPFGSFYFIVPQVEFNELGGSSMLAATIAWDdalSWTWE 221

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 143 -ALNDLMDLFNNISDIDV---DEQIGE--ITRNEDIYKDDWRQLVVEAIESINNEE----KIVLARRRLIKFDKDISIPY 212
Cdd:PLN02786  222 nAIEALQETMLQVSSVVMklrKESLGVsvLSKNHVPSKGAWHLAVNKALQIIKRKSsplkKVVLARSSRIITDTDIDPIA 301

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 213 ILKQAYSKEKNSYIFLLESQD-SIFFSQTPEQLIKVNNKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVV 291
Cdd:PLN02786  302 WLACLQVEGQNAYQFCLQPPDaPAFIGNTPEQLFHRKGLGVCSEALAATRPRGGSSARDLQIELDLLTSPKDDLEFSIVR 381

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 292 DSILHDIKPYITELHYDKTPKILKNDHLYHLYTEIKAPL--KDDSYiSLIDHLHPTPALGGYPKEFAMDFIEQKEFGTRG 369
Cdd:PLN02786  382 ENIREKLEAICDRVVVEPHKAIRKLARVQHLYAQLAGRLrsEDDEF-DILAALHPTPAVCGHPTEEARLLIAETESFDRG 460

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2096088362 370 LYGAPVGYIDiYDDCEFIVAIRSMLIKK-AQATLFAGCGIVKDSDPDSELAETNLK 424
Cdd:PLN02786  461 MYAGPVGWFG-GGESEFAVGIRSALVEKgLGALIYAGTGIVEGSNPSSEWNELELK 515
PRK15016 PRK15016
isochorismate synthase EntC; Provisional
 192-434 9.55e-33

isochorismate synthase EntC; Provisional


Pssm-ID: 184977 [Multi-domain]  Cd Length: 391  Bit Score: 127.68  E-value: 9.55e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 192 EKIVLARRRLIKFDKDISIPYILKQAYSKEKNSYIFLLESQDS-IFFSQTPEQLIKVNNKILSTKAVAGTIKRSQDEDED 270
Cdd:PRK15016  146 DKVVLSRLIDITTDAAIDSGALLERLIAQNPVSYNFHVPLADGgVLLGASPELLLRKDGERFSSLPLAGSARRQPDEVLD 225

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 271 TKNVEAFLKDNKNLIEHRFVVDSILHDIKPYITELHYDKTPKILKNDHLYHLYTEIKA-PLKDDSYISLIDHLHPTPALG 349
Cdd:PRK15016  226 REAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGkANAQENALTLACLLHPTPALS 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 350 GYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKKAQATLFAGCGIVKDSDPDSELAETNLKFTPMM 429
Cdd:PRK15016  306 GFPHQAAKQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTML 385


                  ....*
gi 2096088362 430 NALGV 434
Cdd:PRK15016  386 NVFGL 390
TrpE COG0147
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ...
 174-434 6.42e-32

Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 439917 [Multi-domain]  Cd Length: 416  Bit Score: 125.60  E-value: 6.42e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 174 KDDWRQLVVEAIESINNEE--KIVLARRRLIKFDKDisiPYilkQAYSK--EKNS--YIFLLESQDSIFFSQTPEQLIKV 247
Cdd:COG0147   153 REEYLAAVERAKEYIRAGDifQVVLSQRFSAPFEGD---PL---ALYRAlrRINPspYMFYLRFGDFAIVGSSPERLVRV 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 248 NNKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDI----KP---YITELHydktpKILKNDHLY 320
Cdd:COG0147   227 EDGRVETRPIAGTRPRGATPEEDAALAEELLADEKERAEHLMLVDLARNDLgrvcEPgsvKVPELM-----VVERYSHVM 301

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 321 HLYTEIKAPLKDDsyISLIDHLHPT-PA--LGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKK 397
Cdd:COG0147   302 HLVSTVTGRLRPG--LDALDALRATfPAgtLTGAPKIRAMEIIDELEPTRRGVYGGAVGYLSFDGNMDLAIAIRTAVVKD 379

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 2096088362 398 AQATLFAGCGIVKDSDPDSELAETNLKFTPMMNALGV 434
Cdd:COG0147   380 GRAYVQAGAGIVADSDPEAEYQETLNKARALLRALEL 416
PRK13567 PRK13567
anthranilate synthase component I; Provisional
 225-424 1.23e-30

anthranilate synthase component I; Provisional


Pssm-ID: 184148 [Multi-domain]  Cd Length: 468  Bit Score: 122.95  E-value: 1.23e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 225 YIFLLESQDSIFFSQTPEQLIKVNNKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDI----KP 300
Cdd:PRK13567  257 YMYYLNIDQPYIVGSSPESFVSVKDQIVTTNPIAGTIQRGETTQIDNENMKQLLNDPKECSEHRMLVDLGRNDIhrvsKI 336

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 301 YITELhyDKTPKILKNDHLYHLYTEIKAPLKDD-SYISLIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYID 379
Cdd:PRK13567  337 GTSKI--TKLMVIEKYEHVMHIVSEVTGKINQNlSPMTVIANLLPTGTVSGAPKLRAIERIYEQYPHKRGVYSGGVGYIN 414

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2096088362 380 IYDDCEFIVAIRSMLIKKAQATLFAGCGIVKDSDPDSELAETNLK 424
Cdd:PRK13567  415 CNHNLDFALAIRTMMIDEQYINVEAGCGVVYDSIPEKELNETKLK 459
PRK15012 PRK15012
menaquinone-specific isochorismate synthase; Provisional
 174-424 9.02e-30

menaquinone-specific isochorismate synthase; Provisional


Pssm-ID: 184974 [Multi-domain]  Cd Length: 431  Bit Score: 119.95  E-value: 9.02e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 174 KDDWRQLVVEAIESINNEE--KIVLARRRLIKFDKDISIPYILKQAYSKEKNSYIFLLE-SQDSIFFSQTPEQLIKVNNK 250
Cdd:PRK15012  169 KTGWTQLIELATKTIAEGEldKVVLARATDLHFASPVNAAAMMAASRRLNLNCYHFYMAfDAENAFLGSSPERLWRRRDK 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 251 ILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKPYITELHYdKTPKILKNDHLYHL----YTEI 326
Cdd:PRK15012  249 ALRTEALAGTVANHPDDKQAQQLGEWLMADDKNQRENMLVVEDICQRLQADTQTLDV-LPPQVLRLRKVQHLrrciWTSL 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 327 KAPlkDDSYISLidHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIyDDCEFIVAIRSMLIKKAQATLFAGC 406
Cdd:PRK15012  328 NKA--DDVICLH--QLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSL-QQSEFCVSLRSAKVSGNVVRLYAGA 402

                         250
                  ....*....|....*...
gi 2096088362 407 GIVKDSDPDSELAETNLK 424
Cdd:PRK15012  403 GIVRGSDPEQEWQEIDNK 420
PRK13572 PRK13572
anthranilate synthase component I; Provisional
 171-434 6.74e-29

anthranilate synthase component I; Provisional


Pssm-ID: 237432 [Multi-domain]  Cd Length: 435  Bit Score: 117.53  E-value: 6.74e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 171 DIYKDDWRQLVVEAIESINNEE--KIVLARRRLIkfDKDISIPYILKQAYSKEKNSYIFLLESqDSIFFSQTPEQLIKVN 248
Cdd:PRK13572  169 DADREEFVEMVEKAKEYIYSGDvfQVVLSREYRL--KTDLSPFQLYRNLREINPSPYMFLLEF-DKDVVGASPETMASVE 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 249 NKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDI----KPYITELhyDKTPKILKNDHLYHLYT 324
Cdd:PRK13572  246 NNILKINPIAGTAPRGKTEEEDKKLAEALLSDEKERAEHVMLVDLARNDVrkvsKSGSVRL--ERFFDVVKYSHVQHIES 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 325 EIKAPLKDDSYI-SLIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKKaQATLF 403
Cdd:PRK13572  324 EVVGELKEDSTMfDAIEAAFPAGTLTGAPKFRAMEIIDELEKSRRKVYGGAVGYFSNSGNADLAIAIRMAEIDK-VCRVR 402

                         250       260       270
                  ....*....|....*....|....*....|.
gi 2096088362 404 AGCGIVKDSDPDSELAETNLKFTPMMNALGV 434
Cdd:PRK13572  403 AGAGIVADSVPEKEFYETERKMAAVLKALGV 433
PRK13574 PRK13574
anthranilate synthase component I; Provisional
 170-434 2.71e-24

anthranilate synthase component I; Provisional


Pssm-ID: 184155 [Multi-domain]  Cd Length: 420  Bit Score: 104.13  E-value: 2.71e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 170 EDIYKDDWRQLVVEAIESINNEE--KIVLARRRLIKFDKD-ISIPYILKQAyskEKNSYIFLLESQDSIFFSQTPEQLIK 246
Cdd:PRK13574  153 ESLNKNNYEKIVSESLEYIRSGYifQVVLSRFYRYLFSGDpLRIYYNLRRI---NPSPYMFYLKFDERYLIGSSPELLFR 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 247 VNNKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKPY-------ITELHYdktpkILKNDHL 319
Cdd:PRK13574  230 VQDNIVETYPIAGTRPRGSDQEEDLKLELELMNSEKDKAEHLMLVDLARNDLGKVcvpgtvrVPELMY-----VEKYSHV 304

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 320 YHLYTEIKAPLKDD-SYISLIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKKA 398
Cdd:PRK13574  305 QHIVSKVIGTLKKKyNALDVLKATFPAGTVSGAPKPMAMNIIETLEEYKRGPYAGAVGFISADGNAEFAIAIRTAFLNKD 384

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 2096088362 399 QATLFAGCGIVKDSDPDSELAETNLKFTPMMNALGV 434
Cdd:PRK13574  385 LLRIQAGAGIVYDSNPESEYFETEHKLRALKTAIGV 420
PRK13571 PRK13571
anthranilate synthase component I; Provisional
 174-434 1.69e-23

anthranilate synthase component I; Provisional


Pssm-ID: 184152 [Multi-domain]  Cd Length: 506  Bit Score: 102.79  E-value: 1.69e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 174 KDDWRQLVVEAIESINNEE--KIVLARRRLIKFDKD-ISIPYILKqaySKEKNSYIFLL---ESQDSIFFS---QTPEQL 244
Cdd:PRK13571  229 VEEFGAAVEKLVEEIRAGEafQVVPSQRFEMDTTADpLDVYRVLR---VTNPSPYMYLLrvpNSDGGTDFSivgSSPEAL 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 245 IKVNNKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDI----KPYITELHydKTPKILKNDHLY 320
Cdd:PRK13571  306 VTVTDGRATTHPIAGTRWRGATPEEDALLEKELLADPKERAEHLMLVDLGRNDLgrvcRPGTVRVV--DFSHIERYSHVM 383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 321 HLYTEIKAPLKDDSyiSLIDHLHPT-PA--LGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKK 397
Cdd:PRK13571  384 HLVSTVTGELAEGR--TALDAVTACfPAgtLSGAPKVRAMELIEELEPTRRGLYGGVVGYLDFAGDADTAIAIRTALMRD 461

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 2096088362 398 AQATLFAGCGIVKDSDPDSELAETNLKFTPMMNALGV 434
Cdd:PRK13571  462 GTAYVQAGGGVVADSDPDYEDNEARNKAAAVLRAIAA 498
PRK06404 PRK06404
anthranilate synthase component I; Reviewed
 181-420 2.48e-22

anthranilate synthase component I; Reviewed


Pssm-ID: 102361 [Multi-domain]  Cd Length: 351  Bit Score: 97.63  E-value: 2.48e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 181 VVEAIESINNEE--KIVLARrrliKFDKDISIPYILKQAYSKEKNSYIFLLESQDSIFFSQTPEQLIKVNNKILSTKAVA 258
Cdd:PRK06404  111 IKELIELIRAGEvlQVVISR----EFEANIDFKEKLSEFINNDRSRYVFYYRFGKYRVVGSSPENVFTVNGNIINVDPIA 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 259 GTIKRSQDEDEdtknveaFLKDNKNLIEHRFVVDSILHDIKPY--ITELHYDKTPKILKNDHLYHLYTEIKAPLKDDSYI 336
Cdd:PRK06404  187 GTYDDKILSNE-------LLNSEKDKLEHRMLLDLARNDLSKFadIGTLNVDKVMKIEEFSSVKHLVSQVTAKFSNASYR 259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 337 SLIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYI--DIYDdceFIVAIRSMLIKKAQATLFAGCGIVKDSDP 414
Cdd:PRK06404  260 DILASMFPAGTVSGSPKERAIEIINKYEETPRGPYGGAIGIIskGYTD---MALVIRTAYSHGNGFRVRAGAGIVKDSDP 336


                  ....*.
gi 2096088362 415 DSELAE 420
Cdd:PRK06404  337 EDEVNE 342
PRK09070 PRK09070
aminodeoxychorismate synthase component I;
238-434 1.22e-18

aminodeoxychorismate synthase component I;


Pssm-ID: 236371 [Multi-domain]  Cd Length: 447  Bit Score: 87.83  E-value: 1.22e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 238 SQTPEQLIKVNNKILSTKAVAGTIKRSQDeDEDTKNVEAFLKDNKNLIEHRFVVDSILHDI----KPYITELhyDKTPKI 313
Cdd:PRK09070  248 SSSPERLVSVQGGVVQTRPIAGTRPRFAG-DDDAALIRELVGHPKERAEHVMLIDLERNDLgricAPGSVEV--DELMTV 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 314 LKNDHLYHLYTEIKAPLKDDSYIS-LIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRS 392
Cdd:PRK09070  325 ESYAHVHHIVSNVRGRLRDGVTPGeVIRAVFPGGTITGCPKVRCMQIIAELEQTPRGAYTGSFGYLNRDGDMDLNILIRT 404

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2096088362 393 MLIKKAQATLFAGCGIVKDSDPDSELAETNLKFTPMMNALGV 434
Cdd:PRK09070  405 AEVQGNQVRFRTGAGIVVDSDPERELDETRAKARGLLRALEQ 446
PRK05940 PRK05940
anthranilate synthase component I;
238-433 1.13e-17

anthranilate synthase component I;


Pssm-ID: 235651 [Multi-domain]  Cd Length: 463  Bit Score: 84.78  E-value: 1.13e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 238 SQTPEQLIKVNNKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKPYIT--ELHYDKTPKILK 315
Cdd:PRK05940  253 SCSPERLVQLQGNQAQTRPIAGTRPRGKTPAEDQQLAEELLSNIKERAEHIMLVDLERNDLGRVCQwgSVEVDELLTIER 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 316 NDHLYHLYTEIKAPL-KDDSYISLIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSML 394
Cdd:PRK05940  333 YSHVIHLVSNVVGTLqPNRDAIDLIRALFPGGTITGCPKVRCMEIIEELEPVRRNLFYGSCGYLDQRGNLDLNILIRTLL 412

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2096088362 395 IKKAQATLF-----AGCGIVKDSDPDSELAETNLKFTPMMNALG 433
Cdd:PRK05940  413 YTPLSRGLStiwgqVGAGIVADSDPEKEWLESLQKAKAQLAALN 456
PRK07508 PRK07508
aminodeoxychorismate synthase component I;
235-424 3.07e-17

aminodeoxychorismate synthase component I;


Pssm-ID: 236035 [Multi-domain]  Cd Length: 378  Bit Score: 82.75  E-value: 3.07e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 235 IFFSQTPEQLIkvnnkilSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKpYITELHYDKTPKIL 314
Cdd:PRK07508  180 LFFRVDGEGWI-------ETHPMKGTAPRGATPAEDARLRAALLNDEKNQAENRMIVDLLRNDIS-RISEVGSLDVPELF 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 315 KNDH---LYHLYTEIKAPLKDDSYISLIDH-LHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAI 390
Cdd:PRK07508  252 DIETyptVHQMVSRVRARLLPGLGLADIFAaLFPCGSITGAPKIRAMEILRELEPGPRDLYCGAIGWIAPDGRMRFNVAI 331

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2096088362 391 RSM-LIKKAQATLFAGCGIVKDSDPDSELAETNLK 424
Cdd:PRK07508  332 RTLsLFPGGRAVFNVGGGIVFDSTAEAEYEECLLK 366
PLN02445 PLN02445
anthranilate synthase component I
 225-421 6.74e-17

anthranilate synthase component I


Pssm-ID: 215244 [Multi-domain]  Cd Length: 523  Bit Score: 82.80  E-value: 6.74e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 225 YIFLLESQDSIFFSQTPEQLIKVNNKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDI----KP 300
Cdd:PLN02445  286 YMIYLQARGCILVASSPEILTRVKKNKIVNRPLAGTRRRGKTPEEDKALEKDLLADEKQCAEHIMLVDLGRNDVgkvsKA 365

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 301 yiTELHYDKTPKILKNDHLYHLYTEIKAPLKDDsyISLIDHLH---PTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGY 377
Cdd:PLN02445  366 --GSVKVEKLMNIERYSHVMHISSTVTGELLDH--LTSWDALRaalPVGTVSGAPKVRAMELIDELEVTRRGPYSGGFGG 441

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2096088362 378 IDIYDDCEFIVAIRSMLIKKAQA--TLF----------------AGCGIVKDSDPDSELAET 421
Cdd:PLN02445  442 VSFTGDMDIALALRTMVFPTAARydTMYsykdtnsrrewvahlqAGAGIVADSDPEDEYREC 503
PRK06772 PRK06772
salicylate synthase;
81-434 1.35e-16

salicylate synthase;


Pssm-ID: 102546 [Multi-domain]  Cd Length: 434  Bit Score: 81.32  E-value: 1.35e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362  81 HPQSEKHHLRVVGGFQFSSHKsddewREFGLNHFVLPevlistdnngtFLTYTVKRESFTVEALNdlMDLFNNISD---- 156
Cdd:PRK06772   86 HPQVKGRRVYGQVGFNFAAHA-----RGIAFNAGEWP-----------LLTLTVPREELIFEKGN--VTVYADSADgcrr 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 157 -IDVDEQIGEITRNEDIYKDD------WRQLVVEAIESINNEEKIVLARRRLIKFDKDISIPYILkqAYSKEKN----SY 225
Cdd:PRK06772  148 lCEWVKEAGTTTQNAPLAVDTalngeaYKQQVARAVAEIRRGEYVKVIVSRAIPLPSRIDMPATL--LYGRQANtpvrSF 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 226 IFLLESQDSIFFSqtPEQLIKVNNKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHrfvvdsiLHDIKPYITEL 305
Cdd:PRK06772  226 MFRQEGREALGFS--PELVMSVTGNKVVTEPLAGTRDRMGNPEHNKAKEAELLHDSKEVLEH-------ILSVKEAIAEL 296

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 306 HYDKTP---------KILKNDHLYHLYTEIKAPLKD--DSYISLIdHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGap 374
Cdd:PRK06772  297 EAVCQPgsvvvedlmSVRQRGSVQHLGSGVSGQLAEnkDAWDAFT-VLFPSITASGIPKNAALNAIMQIEKTPRELYS-- 373

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2096088362 375 vGYIDIYDDCEFIVA--IRSMLIKKAQATLFAGCGIVKDSDPDSELAETNLKFTPMMNALGV 434
Cdd:PRK06772  374 -GAILLLDDTRFDAAlvLRSVFQDSQRCWIQAGAGIIAQSTPERELTETREKLASIAPYLMV 434
PRK13564 PRK13564
anthranilate synthase component 1;
217-421 8.27e-16

anthranilate synthase component 1;


Pssm-ID: 237428 [Multi-domain]  Cd Length: 520  Bit Score: 79.49  E-value: 8.27e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 217 AYSKEKNS----YIFLLESQDSIFFSQTPEQLIKV---NNKIlSTKAVAGTIKR------SQDEDEDTKNvEAFLK-DNK 282
Cdd:PRK13564  280 AYRVLKKSnpspYMFYMQDEDFTLFGASPESALKYdasSRQV-EIYPIAGTRPRgrradgSIDRDLDSRI-ELELRtDHK 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 283 NLIEHRFVVDSILHDI----KP---YITELhydktpkiLKND---HLYHLYTEIKAPLKDDsyislIDHLHPTPA----- 347
Cdd:PRK13564  358 ELAEHLMLVDLARNDLaricQPgsrYVADL--------LKVDrysHVMHLVSRVVGELRHD-----LDALHAYRAcmnmg 424

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2096088362 348 -LGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIY---DDCefIVaIRSMLIKKAQATLFAGCGIVKDSDPDSELAET 421
Cdd:PRK13564  425 tLTGAPKVRAMQLIREVEGQRRGSYGGAVGYLTGHgdlDTC--IV-IRSAFVENGIATVQAGAGVVLDSDPQSEADET 499
pabB PRK15465
aminodeoxychorismate synthase component 1;
228-421 3.29e-13

aminodeoxychorismate synthase component 1;


Pssm-ID: 185362 [Multi-domain]  Cd Length: 453  Bit Score: 71.10  E-value: 3.29e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 228 LLESQDSIFFSQTPEQLIKVNNKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKpYITELHY 307
Cdd:PRK15465  244 FLRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIG-RVAVAGS 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 308 DKTPKILKND---HLYHLYTEIKAPLKDDSYIS-LIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDD 383
Cdd:PRK15465  323 VKVPELFVVEpfpAVHHLVSTITARLPEQLHASdLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGN 402

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2096088362 384 CEFIVAIRSMLIKKAQATLFAGCGIVKDSDPDSELAET 421
Cdd:PRK15465  403 MDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQET 440
PRK07093 PRK07093
para-aminobenzoate synthase component I; Validated
 208-420 4.32e-11

para-aminobenzoate synthase component I; Validated


Pssm-ID: 235932 [Multi-domain]  Cd Length: 323  Bit Score: 63.73  E-value: 4.32e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 208 ISIPYILKQAYSKEKNSYIFLLESQdSIFFSqtPEQLIKVNNKILSTKAVAGTIkrsqdeDEDTKNVEAFLKDN-KNLIE 286
Cdd:PRK07093  103 IETNLSLEEIFQASKAKYKLLFKDQ-FVCFS--PEPFVRIEDNKISTYPMKGTI------DASLPNAEEKLLNDeKEFAE 173

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 287 HRFVVDSILHD-------IK----PYITELHYDKTPkilkndhLYHLYTEIKAPLKDD---SYISLIDHLHPTPALGGYP 352
Cdd:PRK07093  174 HATIVDLLRNDlsmvaknVRvtrfRYIDKIKTNKGE-------ILQTSSEISGTLPENwqeNIGDILAKLLPAGSITGAP 246

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2096088362 353 KEFAMDFIEQKEFGTRGLYGAPVGYID--IYDDCefiVAIRsmLIKKAQATLF--AGCGIVKDSDPDSELAE 420
Cdd:PRK07093  247 KEKTVEIIEQAEGYERGFYTGVFGYFDgeSLDSA---VMIR--FIEQENDGLYfkSGGGITIDSDLKDEYNE 313
PRK07912 PRK07912
salicylate synthase;
176-426 7.43e-11

salicylate synthase;


Pssm-ID: 169151 [Multi-domain]  Cd Length: 449  Bit Score: 63.66  E-value: 7.43e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 176 DWRQLVVEAIESI--NNEEKIVLARRRLIKFDKDISIPYILKQAYSKEKNSYIFLLESQDSIFFSqtPEQLIKVN-NKIL 252
Cdd:PRK07912  185 GYRDRVAVAVAEIaaGRYHKVILSRCVEVPFAVDFPATYRLGRRHNTPVRSFLLRLGGIRALGYS--PELVTAVRaDGVV 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 253 STKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIkpyiTELHYDKTPKIL------KNDHLYHLYTEI 326
Cdd:PRK07912  263 ITEPLAGTRAFGRGAAIDRLARDDLESNSKEIVEHAISVRSSLAEI----TEIAEPGSAAVIdfmtvrERGSVQHLGSTV 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 327 KAPLK-DDSYISLIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKKAQATLFAG 405
Cdd:PRK07912  339 RGRLDaSSDRMDALEALFPAVTASGIPKAAGVDAIFRLDEAPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAG 418

                         250       260
                  ....*....|....*....|.
gi 2096088362 406 CGIVKDSDPDSELAETNLKFT 426
Cdd:PRK07912  419 AGIIEESEPEREFEETCEKLS 439
PRK05877 PRK05877
aminodeoxychorismate synthase component I; Provisional
 238-434 1.05e-09

aminodeoxychorismate synthase component I; Provisional


Pssm-ID: 235634 [Multi-domain]  Cd Length: 405  Bit Score: 60.10  E-value: 1.05e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 238 SQTPEQLIKVNNKILSTKAVAGTIKRSQDEdedtknvEAFLKDNKNLIEHRFVVDSILHDIKpYITELHYDKTPKILKND 317
Cdd:PRK05877  205 SLSPELFLRRRGSVVTSSPIKGTLPLDADP-------SALRASAKDVAENIMIVDLVRNDLG-RVARTGTVTVPELLVVR 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 318 H---LYHLYTEIKAPLKDDSYIS-LIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSM 393
Cdd:PRK05877  277 PapgVWHLVSTVSAQVPDELPMSdLLDATFPPASVTGTPKLRARELISQWEPVRRGIYCGTVGLASPVAGCELNVAIRTV 356

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2096088362 394 LIKKA-QATLFAGCGIVKDSDPDSELAETNLKFTPMMNALGV 434
Cdd:PRK05877  357 EFDADgNAVLGVGGGITADSDPDAEWQECLHKAAPIVGLPAA 398
PRK13566 PRK13566
anthranilate synthase component I;
350-435 1.49e-09

anthranilate synthase component I;


Pssm-ID: 237429 [Multi-domain]  Cd Length: 720  Bit Score: 59.93  E-value: 1.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 350 GYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKKAQATLFAGCGIVKDSDPDSELAETNLKFTPMM 429
Cdd:PRK13566  423 GAPKLWAMQFIEDHERSPRRWYGGAVGMVGFDGDMNTGLTLRTIRIKDGVAEVRVGATLLFDSDPEAEEAETELKASALL 502


                  ....*.
gi 2096088362 430 NALGVD 435
Cdd:PRK13566  503 QALRGA 508
PLN02889 PLN02889
oxo-acid-lyase/anthranilate synthase
 238-432 4.79e-09

oxo-acid-lyase/anthranilate synthase


Pssm-ID: 215481 [Multi-domain]  Cd Length: 918  Bit Score: 58.71  E-value: 4.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 238 SQTPEQLIKVN-NKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKpYITELHYDKTPKILKN 316
Cdd:PLN02889  710 SSSPERFLKLDrNGMLEAKPIKGTIARGSTPEEDEQLKLQLQYSEKDQAENLMIVDLLRNDLG-RVCEPGSVHVPNLMDV 788

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2096088362 317 DHLYHLYTEIKAPL-KDDSYISLIDHLH---PTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRS 392
Cdd:PLN02889  789 ESYTTVHTMVSTIRgKKRSNMSPVDCVRaafPGGSMTGAPKLRSMELLDSLESSSRGIYSGSIGFFSYNQTFDLNIVIRT 868

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 2096088362 393 MLIKKAQATLFAGCGIVKDSDPDSELAETNLKFTPMMNAL 432
Cdd:PLN02889  869 VVIHEGEASIGAGGAIVALSNPEDEYEEMILKTRAPANAV 908
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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