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Conserved domains on  [gi|1154997750|ref|WP_078903071|]
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UbiA family prenyltransferase [Streptomyces toyocaensis]

Protein Classification

UbiA prenyltransferase family protein( domain architecture ID 91)

UbiA prenyltransferase family protein, an aromatic prenyltransferase, plays an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PT_UbiA super family cl00337
UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA ...
 43-330 1.35e-44

UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


The actual alignment was detected with superfamily member cd13964:

Pssm-ID: 469727  Cd Length: 282  Bit Score: 154.28  E-value: 1.35e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154997750  43 WAELLRLPALPTVPG--DALAGAAAAGVRPGPRTLLAIGSSLCLYEAGMALNDWADRAEDAAERPHRPIPSGRIEPSAAL 120
Cdd:cd13964     1 YLQLVRLPNLFTVPAdvLAGAALAGGGLGPVLRLALLLLASVLLYAAGMVLNDVFDAELDARERPERPIPSGRVSRGAAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154997750 121 TAACGLTGAGLLLAARAGRPALAVAAPLAATVWAYDLALKHTPAGPAAMAAARGLD-LLLGAAATGAGTRAALPSAALLG 199
Cdd:cd13964    81 ALGAGLLAAGVALAALVGRLSGLVALLLAAAILLYDAWLKHTPLGPLLMGLCRGLNlLLGASAAAAGGLGPALLAALALG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154997750 200 SHTLAVTAVSRRETTGGSVLAPLAALATTGALTRLVTRRRTRLPAGRRAAAAPGLPGSGPPGTTGVlaaalgaayaataa 279
Cdd:cd13964   161 VYIAGVTYIARGEVHGGPRRLLPLALLAVLLVIGLALALAAPRGGRVLLALLFLALFAAWVGRPLL-------------- 226

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1154997750 280 rpyaHAALNPSPPLTQRAVGGGIRATVPLQAALAARSGSTATSLLIACLVP 330
Cdd:cd13964   227 ----RAYRDPSPPNIGKAVGAGILSLIPLDAALAAAFGGPALALLVLALLP 273
 
Name Accession Description Interval E-value
PT_UbiA_1 cd13964
UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of ...
 43-330 1.35e-44

UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways. The function of this subgroup is unknown.


Pssm-ID: 260127  Cd Length: 282  Bit Score: 154.28  E-value: 1.35e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154997750  43 WAELLRLPALPTVPG--DALAGAAAAGVRPGPRTLLAIGSSLCLYEAGMALNDWADRAEDAAERPHRPIPSGRIEPSAAL 120
Cdd:cd13964     1 YLQLVRLPNLFTVPAdvLAGAALAGGGLGPVLRLALLLLASVLLYAAGMVLNDVFDAELDARERPERPIPSGRVSRGAAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154997750 121 TAACGLTGAGLLLAARAGRPALAVAAPLAATVWAYDLALKHTPAGPAAMAAARGLD-LLLGAAATGAGTRAALPSAALLG 199
Cdd:cd13964    81 ALGAGLLAAGVALAALVGRLSGLVALLLAAAILLYDAWLKHTPLGPLLMGLCRGLNlLLGASAAAAGGLGPALLAALALG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154997750 200 SHTLAVTAVSRRETTGGSVLAPLAALATTGALTRLVTRRRTRLPAGRRAAAAPGLPGSGPPGTTGVlaaalgaayaataa 279
Cdd:cd13964   161 VYIAGVTYIARGEVHGGPRRLLPLALLAVLLVIGLALALAAPRGGRVLLALLFLALFAAWVGRPLL-------------- 226

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1154997750 280 rpyaHAALNPSPPLTQRAVGGGIRATVPLQAALAARSGSTATSLLIACLVP 330
Cdd:cd13964   227 ----RAYRDPSPPNIGKAVGAGILSLIPLDAALAAAFGGPALALLVLALLP 273
UbiA COG0382
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ...
 42-160 8.27e-10

4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440151  Cd Length: 280  Bit Score: 58.70  E-value: 8.27e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154997750  42 AWAELLRLP-----ALPTVPGDALAGAAAAGVRPGPRTLLAIGSSLCLYEAGMALNDWADRAEDA--AERPHRPIPSGRI 114
Cdd:COG0382     2 AYLRLLRLDrpigiLLLLWPTLWALFLAAGGLPDLLLLLLAVLGTVLMRSAGYVINDYFDREIDRinERKPNRPLASGRI 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1154997750 115 EPSAALTAACGLTGAGLLLAARAGRPALAVAAPLAATVWAYDLALK 160
Cdd:COG0382    82 SLREALLLAIVLLLLALALALLLNPLTFLLALAALALAWAYSLFLK 127
prenyl_rel_EboC NF035940
UbiA-like protein EboC;
80-135 3.96e-09

UbiA-like protein EboC;


Pssm-ID: 468273  Cd Length: 292  Bit Score: 56.78  E-value: 3.96e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1154997750  80 SSLCLYEAGMALNDWADRAEDAAERPHRPIPSGRIEPSAALTAACGLTGAGLLLAA 135
Cdd:NF035940   47 ATIGLYGGGVVFNDVFDAELDAVERPERPIPSGRVSKQAALLLGSLLLLIGILAAF 102
PRK07566 PRK07566
chlorophyll synthase ChlG;
90-135 3.82e-08

chlorophyll synthase ChlG;


Pssm-ID: 236052  Cd Length: 314  Bit Score: 54.16  E-value: 3.82e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1154997750  90 ALNDWADRAEDAAERPHRPIPSGRIEPSAALTAACGLTGAGLLLAA 135
Cdd:PRK07566   83 TLNDYFDREVDAINEPYRPIPSGAISLRWVLYLIAVLTVLGLAVAY 128
UbiA pfam01040
UbiA prenyltransferase family;
75-160 1.02e-07

UbiA prenyltransferase family;


Pssm-ID: 460038 [Multi-domain]  Cd Length: 250  Bit Score: 52.23  E-value: 1.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154997750  75 LLAIGSSLCLYEAGMALNDWADRAEDAAER--PHRPIPSGRIEPSAALTAACGLTGAGLLLAARAGRPALAVAAPLAATV 152
Cdd:pfam01040  23 LLALLGTVLARAAANALNDYYDRDIDAIMPrtPNRPLPSGRISPREALIFALVLLALGLLLLLLLNPLTALLGLAALLLY 102


                  ....*...
gi 1154997750 153 WAYDLALK 160
Cdd:pfam01040 103 VLYTLRLK 110
chlor_syn_BchG TIGR01476
bacteriochlorophyll/chlorophyll synthetase; This model describes a subfamily of a large family ...
 90-139 6.25e-06

bacteriochlorophyll/chlorophyll synthetase; This model describes a subfamily of a large family of polyprenyltransferases (pfam01040) that also includes 4-hydroxybenzoate octaprenyltransferase and protoheme IX farnesyltransferase (heme O synthase). Members of this family are found exclusively in photosynthetic organisms, including a single copy in Arabidopsis thaliana. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 130541  Cd Length: 283  Bit Score: 47.08  E-value: 6.25e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1154997750  90 ALNDWADRAEDAAERPHRPIPSGRIEPSAALTAACGLTGAGLLLAARAGR 139
Cdd:TIGR01476  56 SINDYFDRDVDAINEPQRPIPSGIISLREVRWNWLVLTVAGLLVALVLGN 105
 
Name Accession Description Interval E-value
PT_UbiA_1 cd13964
UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of ...
 43-330 1.35e-44

UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways. The function of this subgroup is unknown.


Pssm-ID: 260127  Cd Length: 282  Bit Score: 154.28  E-value: 1.35e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154997750  43 WAELLRLPALPTVPG--DALAGAAAAGVRPGPRTLLAIGSSLCLYEAGMALNDWADRAEDAAERPHRPIPSGRIEPSAAL 120
Cdd:cd13964     1 YLQLVRLPNLFTVPAdvLAGAALAGGGLGPVLRLALLLLASVLLYAAGMVLNDVFDAELDARERPERPIPSGRVSRGAAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154997750 121 TAACGLTGAGLLLAARAGRPALAVAAPLAATVWAYDLALKHTPAGPAAMAAARGLD-LLLGAAATGAGTRAALPSAALLG 199
Cdd:cd13964    81 ALGAGLLAAGVALAALVGRLSGLVALLLAAAILLYDAWLKHTPLGPLLMGLCRGLNlLLGASAAAAGGLGPALLAALALG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154997750 200 SHTLAVTAVSRRETTGGSVLAPLAALATTGALTRLVTRRRTRLPAGRRAAAAPGLPGSGPPGTTGVlaaalgaayaataa 279
Cdd:cd13964   161 VYIAGVTYIARGEVHGGPRRLLPLALLAVLLVIGLALALAAPRGGRVLLALLFLALFAAWVGRPLL-------------- 226

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1154997750 280 rpyaHAALNPSPPLTQRAVGGGIRATVPLQAALAARSGSTATSLLIACLVP 330
Cdd:cd13964   227 ----RAYRDPSPPNIGKAVGAGILSLIPLDAALAAAFGGPALALLVLALLP 273
PT_UbiA_DGGGPS cd13961
Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Digeranylgeranylglyceryl phosphate ...
 72-135 7.81e-11

Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Digeranylgeranylglyceryl phosphate synthase (DGGGPS) transfers a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate, as part of the isoprenoid ether lipid biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260124  Cd Length: 270  Bit Score: 61.75  E-value: 7.81e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1154997750  72 PRTLLAIGSSLCLYEAGMALNDWADRAEDAAERPHRPIPSGRIEPSAALTAACGLTGAGLLLAA 135
Cdd:cd13961    35 LELLLLFLSVFLIAAAGYIINDYFDVEIDRINKPDRPIPSGRISRREALILSILLNALGLILAF 98
UbiA COG0382
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ...
 42-160 8.27e-10

4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440151  Cd Length: 280  Bit Score: 58.70  E-value: 8.27e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154997750  42 AWAELLRLP-----ALPTVPGDALAGAAAAGVRPGPRTLLAIGSSLCLYEAGMALNDWADRAEDA--AERPHRPIPSGRI 114
Cdd:COG0382     2 AYLRLLRLDrpigiLLLLWPTLWALFLAAGGLPDLLLLLLAVLGTVLMRSAGYVINDYFDREIDRinERKPNRPLASGRI 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1154997750 115 EPSAALTAACGLTGAGLLLAARAGRPALAVAAPLAATVWAYDLALK 160
Cdd:COG0382    82 SLREALLLAIVLLLLALALALLLNPLTFLLALAALALAWAYSLFLK 127
prenyl_rel_EboC NF035940
UbiA-like protein EboC;
80-135 3.96e-09

UbiA-like protein EboC;


Pssm-ID: 468273  Cd Length: 292  Bit Score: 56.78  E-value: 3.96e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1154997750  80 SSLCLYEAGMALNDWADRAEDAAERPHRPIPSGRIEPSAALTAACGLTGAGLLLAA 135
Cdd:NF035940   47 ATIGLYGGGVVFNDVFDAELDAVERPERPIPSGRVSKQAALLLGSLLLLIGILAAF 102
PT_UbiA cd13956
UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA ...
 68-162 1.30e-08

UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260119 [Multi-domain]  Cd Length: 271  Bit Score: 55.05  E-value: 1.30e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154997750  68 VRPGPRTLLAIGSSLCLYEAGMALNDWADRAEDAAERPHRPIPSGRIEPSAALTAACGLTGAGLLLAARAGRPALAVAAP 147
Cdd:cd13956    28 GPLPALLLLALLAVFLGAGAGYALNDYTDRELDAINKPDRPLPSGRLSPRQALAFAAALLLVGLALALALGPLALLLLLA 107

                          90
                  ....*....|....*
gi 1154997750 148 LAATVWAYDLALKHT 162
Cdd:cd13956   108 GLLLGLAYSLGLKRL 122
PRK07566 PRK07566
chlorophyll synthase ChlG;
90-135 3.82e-08

chlorophyll synthase ChlG;


Pssm-ID: 236052  Cd Length: 314  Bit Score: 54.16  E-value: 3.82e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1154997750  90 ALNDWADRAEDAAERPHRPIPSGRIEPSAALTAACGLTGAGLLLAA 135
Cdd:PRK07566   83 TLNDYFDREVDAINEPYRPIPSGAISLRWVLYLIAVLTVLGLAVAY 128
UbiA pfam01040
UbiA prenyltransferase family;
75-160 1.02e-07

UbiA prenyltransferase family;


Pssm-ID: 460038 [Multi-domain]  Cd Length: 250  Bit Score: 52.23  E-value: 1.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154997750  75 LLAIGSSLCLYEAGMALNDWADRAEDAAER--PHRPIPSGRIEPSAALTAACGLTGAGLLLAARAGRPALAVAAPLAATV 152
Cdd:pfam01040  23 LLALLGTVLARAAANALNDYYDRDIDAIMPrtPNRPLPSGRISPREALIFALVLLALGLLLLLLLNPLTALLGLAALLLY 102


                  ....*...
gi 1154997750 153 WAYDLALK 160
Cdd:pfam01040 103 VLYTLRLK 110
PT_UbiA_chlorophyll cd13958
Bacteriochlorophyll/chlorophyll synthetase; Chlorophyll synthase catalyzes the last step of ...
 90-135 3.44e-07

Bacteriochlorophyll/chlorophyll synthetase; Chlorophyll synthase catalyzes the last step of chlorophyll (Chl) biosynthesis, the addition of the tetraprenyl (phytyl or geranylgeranyl) side chain. In plant chloroplast, the chlorophyll synthase is located in thylakoid membrane and has been shown to also have a regulatory or channeling function. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260121  Cd Length: 277  Bit Score: 51.08  E-value: 3.44e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1154997750  90 ALNDWADRAEDAAERPHRPIPSGRIEPSAALTAACGLTGAGLLLAA 135
Cdd:cd13958    54 TINDYYDREVDAINEPYRPIPSGRISEREALWNIWVLLLLSLLVAL 99
ubiA PRK12882
prenyltransferase; Reviewed
 70-134 2.16e-06

prenyltransferase; Reviewed


Pssm-ID: 183811  Cd Length: 276  Bit Score: 48.43  E-value: 2.16e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1154997750  70 PGPRTLLAIGSSLCLYEAGMALNDWADRAEDAAERPHRPIPSGRIEPSAALTAACGLTGAGLLLA 134
Cdd:PRK12882   36 SPSLTGLAFAAVFLATGAGNAINDYFDREIDRINRPDRPIPSGAVSPRGALAFSILLFAAGVALA 100
chlor_syn_BchG TIGR01476
bacteriochlorophyll/chlorophyll synthetase; This model describes a subfamily of a large family ...
 90-139 6.25e-06

bacteriochlorophyll/chlorophyll synthetase; This model describes a subfamily of a large family of polyprenyltransferases (pfam01040) that also includes 4-hydroxybenzoate octaprenyltransferase and protoheme IX farnesyltransferase (heme O synthase). Members of this family are found exclusively in photosynthetic organisms, including a single copy in Arabidopsis thaliana. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 130541  Cd Length: 283  Bit Score: 47.08  E-value: 6.25e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1154997750  90 ALNDWADRAEDAAERPHRPIPSGRIEPSAALTAACGLTGAGLLLAARAGR 139
Cdd:TIGR01476  56 SINDYFDRDVDAINEPQRPIPSGIISLREVRWNWLVLTVAGLLVALVLGN 105
PT_UbiA_2 cd13963
UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of ...
 91-135 1.67e-05

UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways. The function of this subgroup is unknown.


Pssm-ID: 260126  Cd Length: 278  Bit Score: 45.93  E-value: 1.67e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1154997750  91 LNDWADRAEDAA--ERPHRPIPSGRIEPSAALTAACGLTGAGLLLAA 135
Cdd:cd13963    52 LNDLLDLEADRLhpTKRNRPIASGRLSIPAALALAVVLLLAGLALAL 98
PT_UbiA_COQ2 cd13959
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ...
 87-135 4.47e-05

4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260122 [Multi-domain]  Cd Length: 272  Bit Score: 44.38  E-value: 4.47e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1154997750  87 AGMALNDWADRAEDAA-ERP-HRPIPSGRIEPSAALTAACGLTGAGLLLAA 135
Cdd:cd13959    48 AGCTINDIADRDIDAKvPRTkNRPLASGAISVKEALLFLAVQLLLGLALLL 98
ubiA PRK12884
prenyltransferase; Reviewed
 87-135 4.53e-05

prenyltransferase; Reviewed


Pssm-ID: 183812  Cd Length: 279  Bit Score: 44.56  E-value: 4.53e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1154997750  87 AGMALNDWADRAEDAAERPHRPIPSGRIEPSAALTAACGLTGAGLLLAA 135
Cdd:PRK12884   52 SANALNDYFDYEVDRINRPDRPIPSGRISRREALLLAILLFILGLIAAY 100
PRK09573 PRK09573
(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Reviewed
 88-133 2.80e-04

(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Reviewed


Pssm-ID: 181963  Cd Length: 279  Bit Score: 41.87  E-value: 2.80e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1154997750  88 GMALNDWADRAEDAAERPHRPIPSGRIEPSAALTAACGLTGAGLLL 133
Cdd:PRK09573   53 GNVINDIYDIEIDKINKPERPIPSGRISLKEAKIFSITLFIVGLIL 98
PLN00012 PLN00012
chlorophyll synthetase; Provisional
 91-135 3.90e-04

chlorophyll synthetase; Provisional


Pssm-ID: 215028  Cd Length: 375  Bit Score: 41.77  E-value: 3.90e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1154997750  91 LNDWADRAEDAAERPHRPIPSGRIEPSAALTAACGLTGAGLLLAA 135
Cdd:PLN00012  142 INDWYDREIDAINEPYRPIPSGAISENEVITQIWVLLLGGLGLAY 186
PRK12324 PRK12324
decaprenyl-phosphate phosphoribosyltransferase;
91-134 9.19e-04

decaprenyl-phosphate phosphoribosyltransferase;


Pssm-ID: 237058  Cd Length: 295  Bit Score: 40.62  E-value: 9.19e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1154997750  91 LNDWADRAEDAA--ERPHRPIPSGRIEPSAALTAACGLTGAGLLLA 134
Cdd:PRK12324   65 VNDIRDVEADRLhpTKRNRPIASGVVSVSLAYILAVVLLVASLALA 110
PT_UbiA_3 cd13965
UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of ...
 98-156 1.35e-03

UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways. The function of this subgroup is unknown.


Pssm-ID: 260128  Cd Length: 273  Bit Score: 39.94  E-value: 1.35e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1154997750  98 AEDAAERPHRPIPSGRIEPSAALTAACGLTGAGLLLAARAGrpALAVAAPLAATVWAYD 156
Cdd:cd13965    62 EEDRINKPWRPIPSGRITPRQARRLRWLLVPLCLALSAYLG--VLEESLLLIVLTWLYN 118
PRK04375 PRK04375
protoheme IX farnesyltransferase; Provisional
 70-133 2.54e-03

protoheme IX farnesyltransferase; Provisional


Pssm-ID: 235293  Cd Length: 296  Bit Score: 38.97  E-value: 2.54e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1154997750  70 PGPRTLLA--IGSSLCLYEAGmALNDWADRAEDAA-ERP-HRPIPSGRIEPSAALTAACGLTGAGLLL 133
Cdd:PRK04375   41 PPLLLLLLtlLGIALVAGAAG-ALNNYIDRDIDAKmERTkNRPLVTGRISPREALIFGLVLGVLGFLL 107
PT_UbiA_Cox10 cd13957
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O ...
 74-135 2.68e-03

Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O synthase, heme A:farnesyltransferase, cytochrome c oxidase subunit X [Cox10]) converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of the heme B porphyrin ring with a hydroxyethyl farnesyl side group. It is localized at the mitochondrial inner membrane. Eukaryotic Cox10 is important for the maturation of the heme A prosthetic group of cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, that catalyzes the electron transfer from reduced cytochrome c to oxygen. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260120  Cd Length: 271  Bit Score: 38.96  E-value: 2.68e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1154997750  74 TLLAIGSSlclyeagMALNDWADRAEDAA-ERP-HRPIPSGRIEPSAALTAACGLTGAGLLLAA 135
Cdd:cd13957    40 TALVSASA-------NALNQYIERDIDAKmKRTrNRPLPSGRISPKHALIFGLVLGILGLALLA 96
ubiA PRK12871
prenyltransferase; Reviewed
 85-120 7.52e-03

prenyltransferase; Reviewed


Pssm-ID: 106000  Cd Length: 297  Bit Score: 37.87  E-value: 7.52e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1154997750  85 YEAGMALNDWADRAEDAAE---------RP--HRPIPSGRIEPSAAL 120
Cdd:PRK12871   54 FEAGFVLNDYVDRKRDRLDventltrywRPfkERPIPSGKLSSKNAF 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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