|
Name |
Accession |
Description |
Interval |
E-value |
| HrpA |
COG1643 |
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]; |
1-858 |
0e+00 |
|
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441249 [Multi-domain] Cd Length: 836 Bit Score: 986.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 1 MLHDLSALPIDDVLPAIRAALEASCNLVVVAPPGAGKTTRAPLALLDADWAKGGKLILLEPRRLAARAAASRMAATLGEA 80
Cdd:COG1643 3 LITYPPDLPVSAVLPELLAALRAHQVVVLAAPPGAGKTTQLPLALLELGWGAGGRIGMLEPRRLAARAAAERMAEELGEP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 81 VGETIGLRMRLESKISARTRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALALDAQAGLREDLRLIAM 160
Cdd:COG1643 83 VGETVGYRVRFEDKVSAATRIEVVTEGILLRELQRDPELEGVDTVIFDEFHERSLNADLLLALLLDLQPALRPDLKLLVM 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 161 SATLDGARVAALMG-AKTIESQGRAFGVETRYLGRDANAR-IDEAMTRAILLALREERGSILAFLPGQGEIMRVASRLAE 238
Cdd:COG1643 163 SATLDAERFARLLGdAPVIESSGRTYPVEVRYRPLPADERdLEDAVADAVREALAEEPGDILVFLPGEREIRRTAEALRG 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 239 sRLPDDVDVAPLYGALDRGEQDRAIAPARPGRRKIVLATSIAETSLTIEGVRIVIDSGLARVQRFEPDLGLSRLETVRAS 318
Cdd:COG1643 243 -RLPPDTEILPLYGRLSAAEQDRAFAPAPHGRRRIVLATNIAETSLTVPGIRYVIDSGLARIPRYDPRSGVTRLPTERIS 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 319 RASVDQRRGRAGRTEPGVCYRLWDEPQTAALPAFAAPEILDADLSGLALDLAAWGVSDPAQLKWLDLPPAPAWKEAVALD 398
Cdd:COG1643 322 QASANQRAGRAGRLAPGICYRLWSEEDFARRPAFTDPEILRADLASLILELAAWGLGDPEDLPFLDPPPARAIADARALL 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 399 RELGALD-DGRLTDMGRAMRALPLAPRLARMVVEAADHGEAKRAAELAMLLSERVI--GGADADLSHRVERLHGENSKRA 475
Cdd:COG1643 402 QELGALDaDGRLTPLGRALARLPLDPRLARMLLAAAELGCLREAAILAALLSERDPrrGAAGSDLLARLNLWRRLREQQR 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 476 RDALRLaaqwarqamaaaarspslqspactvegadpALPAANR--RSFASPLPRSGGGTGRGLLSDGALIALAYPDRIAK 553
Cdd:COG1643 482 EFLSYL------------------------------RLREWRDlaRQLRRLLGEGANEEPADYEAIGLLLALAYPDRIAR 531
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 554 SRGARGEFLMANGRAAVLPIEDPLSRAPFLAVAELTGRAAQARILAACALTAEEVEAIAGERIETRDETVFDAANASLRR 633
Cdd:COG1643 532 RRGEGGRYLLARGRGAALFPGSPLAKKEWLVAAELVGGAAEARIRLAAPIDPEWLEELAAHLIKRYSEPHWDKKRGRVVA 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 634 RAFRRLGAIRLSERNLAVEASDQNARILARGAAAVGVARLPWTKSQMQRRDRVAFLRRAEGDEWPDLSEAALAASAEEWL 713
Cdd:COG1643 612 RERVRLGALVLVSRPLPGPDPEAAREALLRALRREGLDLLPWSKAARQLRARVEFLERKLGERWPDVSDEALLATLEDWL 691
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 714 APFIAGRTSLADIAADELEAALVQLLPYELSRRLDVEAPSHFETPAGARHALDYSTENGPiLSVRVQELYGLSSHPTLAR 793
Cdd:COG1643 692 APYLTGVRSLKDLKRLDLLAALRALLPWEQQQRLDELAPTHLTVPSGSRLPLDYSADGPP-VAVRLQELFGLAETPGVAD 770
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 658423197 794 GRAPLTLELLSPAHRPIQTTRDLPSFWKGSWSEVKKEMRGRYPRHLWPDDPAAAQPTTRAKPRGS 858
Cdd:COG1643 771 GRVPVPLHLLSPAGRPLQVTWDLPGFWRGSYAEVRKELRGRYPKHPWPDDPAAAAPTRRTKRRMP 835
|
|
| DEAH_box_HrpB |
TIGR01970 |
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but ... |
8-857 |
0e+00 |
|
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273901 [Multi-domain] Cd Length: 819 Bit Score: 827.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 8 LPIDDVLPAIRAALEASCNLVVVAPPGAGKTTRAPLALLDADWAkGGKLILLEPRRLAARAAASRMAATLGEAVGETIGL 87
Cdd:TIGR01970 1 LPIHAVLPALRDALAAHPQVVLEAPPGAGKSTAVPLALLDAPGI-GGKIIMLEPRRLAARSAAQRLASQLGEAVGQTVGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 88 RMRLESKISARTRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALALDAQAGLREDLRLIAMSATLDGA 167
Cdd:TIGR01970 80 RVRGENKVSRRTRLEVVTEGILTRMIQDDPELDGVGALIFDEFHERSLDADLGLALALDVQSSLREDLKILAMSATLDGE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 168 RVAALMG-AKTIESQGRAFGVETRYLGRDANARIDEAMTRAILLALREERGSILAFLPGQGEIMRVASRLAEsRLPDDVD 246
Cdd:TIGR01970 160 RLSSLLPdAPVVESEGRSFPVEIRYLPLRGDQRLEDAVSRAVEHALASETGSILVFLPGQAEIRRVQEQLAE-RLDSDVL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 247 VAPLYGALDRGEQDRAIAPARPGRRKIVLATSIAETSLTIEGVRIVIDSGLARVQRFEPDLGLSRLETVRASRASVDQRR 326
Cdd:TIGR01970 239 ICPLYGELSLAAQDRAIKPDPQGRRKVVLATNIAETSLTIEGIRVVIDSGLARVARFDPKTGITRLETVRISQASATQRA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 327 GRAGRTEPGVCYRLWDEPQTAALPAFAAPEILDADLSGLALDLAAWGVSDPAQLKWLDLPPAPAWKEAVALDRELGALD- 405
Cdd:TIGR01970 319 GRAGRLEPGVCYRLWSEEQHQRLPAQDEPEILQADLSGLALELAQWGAKDPSDLRWLDAPPSVALAAARQLLQRLGALDa 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 406 DGRLTDMGRAMRALPLAPRLARMVVEAADHGEAKRAAELAMLLSERVI-GGADADLSHRVERLHGENSKRARDALRLAAQ 484
Cdd:TIGR01970 399 QGRLTAHGKAMAALGCHPRLAAMLLSAHSTGLAALACDLAALLEERGLpRQGGADLMNRLHRLQQGRQGRGQRAQQLAKK 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 485 WARQAMAAAARSPSLQSPACtvegadpalpaanrrsfasplprsgggtgrgllsdGALIALAYPDRIAKSRGARGEFLMA 564
Cdd:TIGR01970 479 LRRRLRFSQADSGAIASHAL-----------------------------------GLLLALAFPDRIAKRRGQPGRYQLA 523
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 565 NGRAAVLPIEDPLSRAPFLAVAELTGRAAQ--ARILAACALTAEEVEAIAGERIETRDETVFDAANASLRRRAFRRLGAI 642
Cdd:TIGR01970 524 NGRGAVLSAEDALAREPWLVAADLGEGQGKtaARILLAAPVDEALLRQVLPDLVVQVDQVDWDETKGRLVAERQLRIGQL 603
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 643 RLSERNLAVEASDQNARILARGAAAVGVARLPWTKSQMQRRDRVAFLRRAEGDE-WPDLSEAALAASAEEWLAPFIAGRT 721
Cdd:TIGR01970 604 VLKSEPLANPDPAQIAAALLNYVRQKGLSALNWTEELRQWRARVACARSWDPEAdWPDLSDEALLARLETWLEPYLAGVT 683
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 722 SLADIAADELEAALVQLLPYELSRRLDVEAPSHFETPAGARHALDYSTENGPILSVRVQELYGLSSHPTLARGRAPLTLE 801
Cdd:TIGR01970 684 SLSGLQELDLYDALKNLLPWELQQALDALLPTHWPVPTGNFIAIRYSLDGPPLLAVRLQELFGLAESPRVAQGRVPLTLE 763
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*.
gi 658423197 802 LLSPAHRPIQTTRDLPSFWKGSWSEVKKEMRGRYPRHLWPDDPAAAQPTTRAKPRG 857
Cdd:TIGR01970 764 LLSPAQRPLQVTRDLASFWAGAYREVKKEMKGRYPKHVWPDDPANAAPTKRTKPRG 819
|
|
| PRK11664 |
PRK11664 |
ATP-dependent RNA helicase HrpB; Provisional |
5-854 |
0e+00 |
|
ATP-dependent RNA helicase HrpB; Provisional
Pssm-ID: 236950 [Multi-domain] Cd Length: 812 Bit Score: 747.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 5 LSALPIDDVLPAIRAALEASCNLVVVAPPGAGKTTRAPLALLdADWAKGGKLILLEPRRLAARAAASRMAATLGEAVGET 84
Cdd:PRK11664 1 MSSLPVAAVLPELLTALKTAPQVLLKAPTGAGKSTWLPLQLL-QHGGINGKIIMLEPRRLAARNVAQRLAEQLGEKPGET 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 85 IGLRMRLESKISARTRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALALDAQAGLREDLRLIAMSATL 164
Cdd:PRK11664 80 VGYRMRAESKVGPNTRLEVVTEGILTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 165 DGARVAALM-GAKTIESQGRAFGVETRYLGRDANARIDEAMTRAILLALREERGSILAFLPGQGEIMRVASRLAEsRLPD 243
Cdd:PRK11664 160 DNDRLQQLLpDAPVIVSEGRSFPVERRYQPLPAHQRFDEAVARATAELLRQESGSLLLFLPGVGEIQRVQEQLAS-RVAS 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 244 DVDVAPLYGALDRGEQDRAIAPARPGRRKIVLATSIAETSLTIEGVRIVIDSGLARVQRFEPDLGLSRLETVRASRASVD 323
Cdd:PRK11664 239 DVLLCPLYGALSLAEQQKAILPAPAGRRKVVLATNIAETSLTIEGIRLVVDSGLERVARFDPKTGLTRLVTQRISQASMT 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 324 QRRGRAGRTEPGVCYRLWDEPQTAALPAFAAPEILDADLSGLALDLAAWGVSDPAQLKWLDLPPAPAWKEAVALDRELGA 403
Cdd:PRK11664 319 QRAGRAGRLEPGICLHLYSKEQAERAAAQSEPEILHSDLSGLLLELLQWGCHDPAQLSWLDQPPAAALAAAKRLLQQLGA 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 404 LDD-GRLTDMGRAMRALPLAPRLARMVVEAADHGEA--KRAAELAMLLSERVIGGAdADLSHRVERLHGENSKRARDALR 480
Cdd:PRK11664 399 LDGqGRLTARGRKMAALGNDPRLAAMLVAAKEDDEAalATAAKLAAILEEPPRSGS-SDLGVALSRKQPHWQQRAQQLLK 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 481 LaaqwarqamaaaarspslqspactvegadpalpaanrrsfaspLPRSGGGTGRGLLsdGALIALAYPDRIAKSRGARGE 560
Cdd:PRK11664 478 R-------------------------------------------LNVRGGEADSSLI--APLLALAFPDRIARRRGQDGR 512
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 561 FLMANGRAAVLPIEDPLSRAPFLAVAEL--TGRAAQARILAACALTAEEVEAIAGERIETRDETVFDAANASLRRRAFRR 638
Cdd:PRK11664 513 YQLANGMGAMLDADDALSRHEWLIAPLLlqGSASPDARILLALPLDIDELVQRCPQLVQQSDTVEWDEAKGTLRAWRRLQ 592
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 639 LGAIRLSERNLAVEASDQNARILARGAAAVGVARLPWTKSQMQRRDRvafLRRA-----EGDeWPDLSEAALAASAEEWL 713
Cdd:PRK11664 593 IGQLTVKVQPLAKPSEEELHQALLNWIRRKGLSVLNWTPEAEQLRLR---LLCAakwlpEYD-WPAVDDESLLASLETWL 668
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 714 APFIAGRTSLADIAADELEAALVQLLPYELSRRLDVEAPSHFETPAGARHALDYSTENGPILSVRVQELYGLSSHPTLAR 793
Cdd:PRK11664 669 LPHMTGVRSLRGLKSLNIAQALRGLLDWPQRQRLDSELPTHYTVPTGSRIAIRYHEDNPPALAVRMQEMFGEAQSPTIAQ 748
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 658423197 794 GRAPLTLELLSPAHRPIQTTRDLPSFWKGSWSEVKKEMRGRYPRHLWPDDPAAAQPTTRAK 854
Cdd:PRK11664 749 GRVPLVLELLSPAQRPLQITRDLAAFWQGAYREVQKEMKGRYPKHVWPDDPANTAPTRRTK 809
|
|
| PRK11131 |
PRK11131 |
ATP-dependent RNA helicase HrpA; Provisional |
8-436 |
3.63e-64 |
|
ATP-dependent RNA helicase HrpA; Provisional
Pssm-ID: 182986 [Multi-domain] Cd Length: 1294 Bit Score: 234.95 E-value: 3.63e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 8 LPI----DDVLPAIRAAleascNLVVVA-PPGAGKTTRAPLALLDADWAKGGKLILLEPRRLAARAAASRMAATLGEAVG 82
Cdd:PRK11131 73 LPVsqkkQDILEAIRDH-----QVVIVAgETGSGKTTQLPKICLELGRGVKGLIGHTQPRRLAARTVANRIAEELETELG 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 83 ETIGLRMRLESKISARTRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDAD--LGLALALDAQaglREDLRLIAM 160
Cdd:PRK11131 148 GCVGYKVRFNDQVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDfiLGYLKELLPR---RPDLKVIIT 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 161 SATLDGARVAA-LMGAKTIESQGRAFGVETRY--LGRDANARiDEAMTRAILLAL----REERGSILAFLPGQGEIMRVA 233
Cdd:PRK11131 225 SATIDPERFSRhFNNAPIIEVSGRTYPVEVRYrpIVEEADDT-ERDQLQAIFDAVdelgREGPGDILIFMSGEREIRDTA 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 234 SRLAESRLPDdVDVAPLYGALDRGEQDRAIAPArpGRRKIVLATSIAETSLTIEGVRIVIDSGLARVQRFEPDLGLSRLE 313
Cdd:PRK11131 304 DALNKLNLRH-TEILPLYARLSNSEQNRVFQSH--SGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLP 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 314 TVRASRASVDQRRGRAGRTEPGVCYRLWDEPQTAALPAFAAPEILDADLSGLALDLAAWGVSDPAQLKWLDLPPAPAWKE 393
Cdd:PRK11131 381 IEPISQASANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPDKRNIQD 460
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 658423197 394 AVALDRELGALDDG------RLTDMGRAMRALPLAPRLARMVVEAADHG 436
Cdd:PRK11131 461 GVRLLEELGAITTDeqasayKLTPLGRQLAQLPVDPRLARMVLEAQKHG 509
|
|
| HrpB_C |
pfam08482 |
ATP-dependent helicase C-terminal; This domain is found near the C-terminus of bacterial ... |
719-843 |
3.09e-62 |
|
ATP-dependent helicase C-terminal; This domain is found near the C-terminus of bacterial ATP-dependent helicases such as HrpB.
Pssm-ID: 430021 [Multi-domain] Cd Length: 126 Bit Score: 205.75 E-value: 3.09e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 719 GRTSLADIAADELEAALVQLLPYELSRRLDVEAPSHFETPAGARHALDYSTENG-PILSVRVQELYGLSSHPTLARGRAP 797
Cdd:pfam08482 1 GVRSLADLKRLDLLAALRALLPWEQQQRLDRLAPEHLTVPSGSRIRIDYSAEGGaPVLAVRLQELFGLAETPRIAGGRVP 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 658423197 798 LTLELLSPAHRPIQTTRDLPSFWKGSWSEVKKEMRGRYPRHLWPDD 843
Cdd:pfam08482 81 LTLHLLSPAGRPVQVTRDLASFWAGSYAEVRKEMRGRYPKHPWPED 126
|
|
| SF2_C_RHA |
cd18791 |
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A ... |
187-341 |
6.82e-60 |
|
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family members are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350178 [Multi-domain] Cd Length: 171 Bit Score: 200.84 E-value: 6.82e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 187 VETRYL----------GRDANARIDEAMTRAIL-LALREERGSILAFLPGQGEIMRVASRL---AESRLPDDVDVAPLYG 252
Cdd:cd18791 3 VEVYYLedilellgisSEKEDPDYVDAAVRLILqIHRTEEPGDILVFLPGQEEIERLCELLreeLLSPDLGKLLVLPLHS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 253 ALDRGEQDRAIAPARPGRRKIVLATSIAETSLTIEGVRIVIDSGLARVQRFEPDLGLSRLETVRASRASVDQRRGRAGRT 332
Cdd:cd18791 83 SLPPEEQQRVFEPPPPGVRKVVLATNIAETSITIPGVVYVIDSGLVKEKVYDPRTGLSSLVTVWISKASAEQRAGRAGRT 162
|
....*....
gi 658423197 333 EPGVCYRLW 341
Cdd:cd18791 163 RPGKCYRLY 171
|
|
| DEXHc_HrpB |
cd17990 |
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA ... |
8-175 |
6.45e-57 |
|
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpB belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438711 [Multi-domain] Cd Length: 174 Bit Score: 192.93 E-value: 6.45e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 8 LPIDDVLPAIRAALEASCNLVVVAPPGAGKTTRAPLALLDADWAKGGKLILLEPRRLAARAAASRMAATLGEAVGETIGL 87
Cdd:cd17990 1 LPIAAVLPALRAALDAGGQVVLEAPPGAGKTTRVPLALLAELWIAGGKIIVLEPRRVAARAAARRLATLLGEAPGETVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 88 RMRLESKISARTRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALALDAQAGLREDLRLIAMSATLDGA 167
Cdd:cd17990 81 RVRGESRVGRRTRVEVVTEGVLLRRLQRDPELSGVGAVILDEFHERSLDADLALALLLEVQQLLRDDLRLLAMSATLDGD 160
|
....*...
gi 658423197 168 RVAALMGA 175
Cdd:cd17990 161 GLAALLPE 168
|
|
| DEXHc_RHA-like |
cd17917 |
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) ... |
27-165 |
1.68e-28 |
|
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438707 [Multi-domain] Cd Length: 159 Bit Score: 111.78 E-value: 1.68e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 27 LVVVAPPGAGKTTRAPLALLDADWAKG--GKLILLEPRRLAARAAASRMAATLGEAVGETIGLRMRLESKISARTRIEVV 104
Cdd:cd17917 4 VVIVGETGSGKTTQVPQFLLEDGLAKGgkGRIVCTQPRRIAAISVAERVAEERGEKLGEEVGYQIRFESKTSSKTRIKFC 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 658423197 105 TEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALALDAQAgLREDLRLIAMSATLD 165
Cdd:cd17917 84 TDGILLRELLSDPLLSGYSHVILDEAHERSLDTDFLLGLLKDLLR-KRPDLKVILMSATLD 143
|
|
| DEXHc_DHX35 |
cd17980 |
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and ... |
8-165 |
6.02e-20 |
|
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and seems to be associated with risk to thyroid cancers. It also has been shown to positively regulate poxviruses, such as Myxoma virus. DEAH-box helicase 35 (DHX35) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350738 [Multi-domain] Cd Length: 185 Bit Score: 88.29 E-value: 6.02e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 8 LPIDDVLPAIRAALEASCNLVVVAPPGAGKTTRAPLALLDADWAKGGKLILL-EPRRLAARAAASRMAATLGEAVGETIG 86
Cdd:cd17980 1 LPVFKLRNHILYLVENYQTIVIVGETGCGKSTQIPQYLAEAGWTAGGRVVGCtQPRRVAAVTVAGRVAEEMGAVLGHEVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 87 LRMRLESKIS-ARTRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALALDAQAgLREDLRLIAMSATLD 165
Cdd:cd17980 81 YCIRFDDCTDpQATRIKFLTDGMLVREMMLDPLLTKYSVIMLDEAHERTLYTDILIGLLKKIQK-KRGDLRLIVASATLD 159
|
|
| DEXHc_DHX57 |
cd17985 |
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the ... |
16-167 |
7.63e-19 |
|
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350743 [Multi-domain] Cd Length: 177 Bit Score: 84.89 E-value: 7.63e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 16 AIRAALEASCNLVVVAPPGAGKTTRAPLALLDaDWAKGG-----KLILLEPRRLAARAAASRMAATLGEAVGETIGLRMR 90
Cdd:cd17985 9 TILELLEKHQVLVISGMTGCGKTTQIPQFILD-NSLQGPplpvaNIICTQPRRISAISVAERVAQERAERVGQSVGYQIR 87
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 658423197 91 LESKISARTRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLgLALALDAQAGLREDLRLIAMSATLDGA 167
Cdd:cd17985 88 LESVKSSATRLLYCTTGVLLRRLEGDPTLQGVTHVIVDEVHERTEESDF-LLLVLKDLMVQRPDLKVILMSATLNAE 163
|
|
| DEXHc_DHX33 |
cd17978 |
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA ... |
8-170 |
1.69e-18 |
|
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA polymerase I transcription of the 47S precursor rRNA. DHX33 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438710 [Multi-domain] Cd Length: 178 Bit Score: 83.94 E-value: 1.69e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 8 LPIDDVLPAIRAALEASCNLVVVAPPGAGKTTRAPLALLDADWAKGGKLILLEPRRLAARAAASRMAATLGEAVGETIGL 87
Cdd:cd17978 1 LPIYSARKRLLEELRKHDTVIIIGETGSGKTTQIPQYLYEAGFARGGMIGITQPRRVAAVSVAKRVAEEMGVELGQLVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 88 RMRLESKISARTRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALALDAQAGLRE----DLRLIAMSAT 163
Cdd:cd17978 81 SVRFDDVTSEETRIKYMTDGMLLREAIGDPLLSKYSVIILDEAHERTVHTDVLFGLVKSAQRRRKEqklsPLKVIIMSAT 160
|
....*..
gi 658423197 164 LDGARVA 170
Cdd:cd17978 161 LDADLFS 167
|
|
| DEXHc_DHX40 |
cd17984 |
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the ... |
8-174 |
1.19e-17 |
|
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350742 [Multi-domain] Cd Length: 178 Bit Score: 81.44 E-value: 1.19e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 8 LPIDDVLPAIRAALEASCNLVVVAPPGAGKTTRAPLALLDADWAKGGKLILLEPRRLAARAAASRMAATLGEAVGETIGL 87
Cdd:cd17984 1 LPIQKQRKKLVQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRRVAAISVAQRVAEEMKCTLGSKVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 88 RMRLESKISARTRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDAD--LGL--ALALDAQAGLREDLRLIAMSAT 163
Cdd:cd17984 81 QVRFDDCSSKETAIKYMTDGCLLRHILADPNLTKYSVIILDEAHERSLTTDilFGLlkKLFQEKSPNRKEHLKVVVMSAT 160
|
170
....*....|.
gi 658423197 164 LDGARVAALMG 174
Cdd:cd17984 161 LELAKLSAFFG 171
|
|
| DEXHc_DHX30 |
cd17976 |
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an ... |
8-174 |
4.33e-17 |
|
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an important role in the assembly of the mitochondrial large ribosomal subunit. DHX30 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350734 [Multi-domain] Cd Length: 178 Bit Score: 79.84 E-value: 4.33e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 8 LPIDDVLPAIRAALEASCNLVVVAPPGAGKTTRAPLALLDaDWAKGGK-----LILLEPRRLAARAAASRMAATLGEAVG 82
Cdd:cd17976 1 LPVDSHKESILSAIEQNPVVVISGDTGCGKTTRIPQFILE-DYVLRGRgarcnVVITQPRRISAVSVAQRVAHELGPNLR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 83 ETIGLRMRLESKISAR-TRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALALDAQAgLREDLRLIAMS 161
Cdd:cd17976 80 RNVGYQVRLESRPPPRgGALLFCTVGVLLKKLQSNPRLEGVSHVIVDEVHERDVNTDFLLILLKGVLQ-LNPELRVVLMS 158
|
170
....*....|...
gi 658423197 162 ATLDGARVAALMG 174
Cdd:cd17976 159 ATGDNQRLSRYFG 171
|
|
| DEXHc_DHX16 |
cd17974 |
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably ... |
27-171 |
4.62e-17 |
|
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably involved in pre-mRNA splicing. DHX16 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350732 [Multi-domain] Cd Length: 174 Bit Score: 79.85 E-value: 4.62e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 27 LVVVAPPGAGKTTRAPLALLDADWAKGGKLI-LLEPRRLAARAAASRMAATLGEAVGETIGLRMRLESKISARTRIEVVT 105
Cdd:cd17974 20 LIIVGETGSGKTTQIPQYLHEAGYTKGGGKIgCTQPRRVAAMSVAARVAEEMGVKLGNEVGYSIRFEDCTSEKTVLKYMT 99
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 658423197 106 EGVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALALDAqAGLREDLRLIAMSATLDGARVAA 171
Cdd:cd17974 100 DGMLLREFLTEPDLASYSVMIIDEAHERTLHTDILFGLVKDI-ARFRPDLKLLISSATMDAEKFSA 164
|
|
| DEXHc_DHX38 |
cd17983 |
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as ... |
27-174 |
1.05e-16 |
|
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as PRP16) is involved in pre-mRNA splicing. DHX38 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350741 [Multi-domain] Cd Length: 173 Bit Score: 78.66 E-value: 1.05e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 27 LVVVAPPGAGKTTRAPLALLDADWAKGGKLILLEPRRLAARAAASRMAATLGEAVGETIGLRMRLESKISARTRIEVVTE 106
Cdd:cd17983 20 VIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGVELGEEVGYAIRFEDCTSENTVIKYMTD 99
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 658423197 107 GVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALaLDAQAGLREDLRLIAMSATLDGARVAALMG 174
Cdd:cd17983 100 GILLRESLRDPDLDKYSAIIMDEAHERSLNTDVLFGL-LREVVARRRDLKLIVTSATMDADKFADFFG 166
|
|
| DEXHc_DHX8 |
cd17971 |
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as ... |
27-168 |
2.27e-16 |
|
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22) acts late in the splicing of pre-mRNA and mediates the release of the spliced mRNA from spliceosomes. DHX8 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350729 [Multi-domain] Cd Length: 179 Bit Score: 77.91 E-value: 2.27e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 27 LVVVAPPGAGKTTRAPLALLDADWAKGGKLILLEPRRLAARAAASRMAATLGEAVGETIGLRMRLESKISARTRIEVVTE 106
Cdd:cd17971 25 LVVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVAEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTD 104
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 658423197 107 GVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALaLDAQAGLREDLRLIAMSATLDGAR 168
Cdd:cd17971 105 GMLLRECLIDPDLSQYSVIMLDEAHERTIHTDVLFGL-LKKTVQKRPDLKLIVTSATLDAVK 165
|
|
| DEXHc_YTHDC2 |
cd17987 |
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) ... |
8-165 |
6.05e-16 |
|
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) regulates mRNA translation and stability via binding to N6-methyladenosine, a modified RNA nucleotide enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. YTHDC2 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350745 [Multi-domain] Cd Length: 176 Bit Score: 76.41 E-value: 6.05e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 8 LPIDDVLPAIRAALEASCNLVVVAPPGAGKTTRAPLALLDADWAKGG--KLILLEPRRLAARAAASRMAATLGEAVGETI 85
Cdd:cd17987 1 LPVFEKQEQIVRIIKENKVVLIVGETGSGKTTQIPQFLLDDCYANGIpcRIFCTQPRRLAAIAVAERVAAERGEKIGQTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 86 GLRMRLESKISARTRIEVVTEGVFARMILD-DAGLEGVAGVLFDEYHERSLDADLgLALALDAQAGLREDLRLIAMSATL 164
Cdd:cd17987 81 GYQIRLESRVSPKTLLTFCTNGVLLRTLMAgDSALSTVTHVIVDEVHERDRFSDF-LLTKLRDILQKHPNLKLILSSAAL 159
|
.
gi 658423197 165 D 165
Cdd:cd17987 160 D 160
|
|
| DEXHc_DHX15 |
cd17973 |
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA ... |
27-165 |
7.47e-14 |
|
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. DHX15 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438709 [Multi-domain] Cd Length: 187 Bit Score: 70.91 E-value: 7.47e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 27 LVVVAPPGAGKTTRAPLALLDADWAK-GGKLI-LLEPRRLAARAAASRMAATLGEAVGETIGLRMRLESKISARTRIEVV 104
Cdd:cd17973 32 LVLVGETGSGKTTQIPQFVLDDELPHqPKKLVaCTQPRRVAAMSVAQRVAEEMDVKLGEEVGYSIRFEDCSSAKTILKYM 111
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 658423197 105 TEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALALDAQAGlREDLRLIAMSATLD 165
Cdd:cd17973 112 TDGMLLREAMSDPLLSRYSVIILDEAHERTLATDILMGLLKEVVRR-RPDLKLIVMSATLD 171
|
|
| DEXHc_HrpA |
cd17989 |
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA ... |
8-170 |
9.60e-14 |
|
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350747 [Multi-domain] Cd Length: 173 Bit Score: 70.18 E-value: 9.60e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 8 LPIDDVLPAIRAALEASCNLVVVAPPGAGKTTRAPLALLDADWAKGGKLILLEPRRLAARAAASRMAATLGEAVGETIGL 87
Cdd:cd17989 1 LPVSQKRDEIAKAIAENQVVIIAGETGSGKTTQLPKICLELGRGIRGLIGHTQPRRLAARSVAERIAEELKTELGGAVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 88 RMRLESKISARTRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALaLDAQAGLREDLRLIAMSATLDGA 167
Cdd:cd17989 81 KVRFTDQTSDETCVKLMTDGILLAETQTDRYLRAYDTIIIDEAHERSLNIDFLLGY-LKQLLPRRPDLKVIITSATIDAE 159
|
...
gi 658423197 168 RVA 170
Cdd:cd17989 160 RFS 162
|
|
| DEXHc_DHX34 |
cd17979 |
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in ... |
8-165 |
1.08e-13 |
|
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in the nonsense-mediated decay (NMD), a surveillance mechanism that degrades aberrant mRNAs. DHX34 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350737 [Multi-domain] Cd Length: 170 Bit Score: 69.78 E-value: 1.08e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 8 LPIDDVLPAIRAALEASCNLVVVAPPGAGKTTRAPLALLDADWakgGKLILLEPRRLAARAAASRMAATLGEAVGETIGL 87
Cdd:cd17979 1 LPIAQYREKIIELLKTHQVVIVAGDTGCGKSTQVPQYLLAAGF---RHIACTQPRRIACISLAKRVAFESLNQYGSKVAY 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 658423197 88 RMRLESKISARTRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALaLDAQAGLREDLRLIAMSATLD 165
Cdd:cd17979 78 QIRFERTRTLATKLLFLTEGLLLRQIQRDASLPQYNVLILDEVHERHLHGDFLLGV-LRCLLRLRPDLKLILMSATIN 154
|
|
| DEXHc_DHX29 |
cd17975 |
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of ... |
27-170 |
4.69e-13 |
|
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of the 43S pre-initiation complex involved in translation initiation of mRNAs with structured 5'-UTRs. DHX29 is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350733 [Multi-domain] Cd Length: 183 Bit Score: 68.40 E-value: 4.69e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 27 LVVVAPPGAGKTTRAPLALLDADWAKGGK-----LILLEPRRLAARAAASRMAATLGEAVG-----ETIGLRMRLESKIS 96
Cdd:cd17975 20 VVVAGETGSGKSTQVPQFLLEDLLLNGGTaqkcnIVCTQPRRISAMSLATRVCEELGCESGpggknSLCGYQIRMESRTG 99
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 658423197 97 ARTRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLgLALALDAQAGLREDLRLIAMSATLDGARVA 170
Cdd:cd17975 100 EATRLLYCTTGVLLRKLQEDGLLSSISHIIVDEVHERSVQSDF-LLIILKEILHKRSDLHLILMSATVDCEKFS 172
|
|
| DEXHc_DHX9 |
cd17972 |
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ... |
1-165 |
7.34e-13 |
|
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ATP-dependent RNA helicase A or RHA and leukophysin or LKP) plays an important role in many cellular processes, including regulation of DNA replication, transcription, translation, microRNA biogenesis, RNA processing and transport, and maintenance of genomic stability. DHX9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350730 [Multi-domain] Cd Length: 234 Bit Score: 69.09 E-value: 7.34e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 1 MLHDLSALPIDDVLPAIRAALEASCNLVVVAPPGAGKTTRAPLALLDaDWAKGGK-----LILLEPRRLAARAAASRMAA 75
Cdd:cd17972 52 ILQERELLPVKKFREEILEAISNNPVVIIRGATGCGKTTQVPQYILD-DFIQNDRaaecnIVVTQPRRISAVSVAERVAF 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 76 TLGEAVGETIGLRMRLESkISAR--TRIEVVTEGVFARMIldDAGLEGVAGVLFDEYHERSLDADLGLALALDAQAGLRe 153
Cdd:cd17972 131 ERGEEVGKSCGYSVRFES-VLPRphASILFCTVGVLLRKL--EAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYP- 206
|
170
....*....|..
gi 658423197 154 DLRLIAMSATLD 165
Cdd:cd17972 207 DLRVILMSATID 218
|
|
| HELICc |
smart00490 |
helicase superfamily c-terminal domain; |
244-331 |
7.28e-12 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 197757 [Multi-domain] Cd Length: 82 Bit Score: 61.84 E-value: 7.28e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 244 DVDVAPLYGALDRGEQDRAIAPARPGRRKIVLATSIAETSLTIEGVRIVIDSGLarvqrfepdlglsrletvRASRASVD 323
Cdd:smart00490 11 GIKVARLHGGLSQEEREEILDKFNNGKIKVLVATDVAERGLDLPGVDLVIIYDL------------------PWSPASYI 72
|
....*...
gi 658423197 324 QRRGRAGR 331
Cdd:smart00490 73 QRIGRAGR 80
|
|
| HA2 |
smart00847 |
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino ... |
400-472 |
1.36e-11 |
|
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 214852 [Multi-domain] Cd Length: 82 Bit Score: 61.13 E-value: 1.36e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 658423197 400 ELGALDD-GRLTDMGRAMRALPLAPRLARMVVEAADHGEakrAAELAMLLSERVIG-----GADADLSHRVERLHGENS 472
Cdd:smart00847 1 ELGALDDdGRLTPLGRKMAELPLDPRLAKMLLAAAEFGC---LDEILTIVAMLSVGdprpkEKREDADAARRRFADPES 76
|
|
| DEXHc_DHX36 |
cd17981 |
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as ... |
28-164 |
2.14e-11 |
|
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as G4-resolvase 1 or G4R1, MLE-like protein 1 and RNA helicase associated with AU-rich element or RHAU) unwinds a G4-quadruplex in human telomerase RNA. DHX36 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350739 [Multi-domain] Cd Length: 180 Bit Score: 63.32 E-value: 2.14e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 28 VVVAPPGAGKTTRAPLALLDaDWAKGGK-----LILLEPRRLAARAAASRMAATLGEAV--GETIGLRMRLESKIS-ART 99
Cdd:cd17981 21 VISGETGCGKTTQVTQFILD-DAIERGKgsscrIVCTQPRRISAISVAERVAAERAESCglGNSTGYQIRLESRKPrKQG 99
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 658423197 100 RIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALALDAqAGLREDLRLIAMSATL 164
Cdd:cd17981 100 SILYCTTGIVLQWLQSDPHLSNVSHLVLDEIHERNLQSDVLMGIVKDL-LPFRSDLKVILMSATL 163
|
|
| DEXHc_DHX37 |
cd17982 |
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the ... |
8-164 |
3.31e-11 |
|
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the human nervous system and has been linked to schizophrenia. It also negatively regulates poxviruses such as Myxoma virus. DEAH-box helicase 37 (DHX37) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350740 [Multi-domain] Cd Length: 191 Bit Score: 63.14 E-value: 3.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 8 LPI----DDVLPAIRAaleascNLVVV--APPGAGKTTRAPLALLDADWAK-----GGKLILLEPRRLAARAAASRMAAT 76
Cdd:cd17982 1 LPIlaeeQEIMEAINE------NPVVIicGETGSGKTTQVPQFLYEAGFGSpesdnPGMIGITQPRRVAAVSMAKRVAEE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 77 LGeAVGETIGLRMRLESKISARTRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLAL---------ALDA 147
Cdd:cd17982 75 LN-VFGKEVSYQIRYDSTVSENTKIKFMTDGVLLKEIQTDFLLRKYSVIIIDEAHERSVNTDILIGMlsrivplraKLYL 153
|
170
....*....|....*..
gi 658423197 148 QAGLREDLRLIAMSATL 164
Cdd:cd17982 154 QDQTVKPLKLVIMSATL 170
|
|
| Helicase_C |
pfam00271 |
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, ... |
244-331 |
4.21e-11 |
|
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
Pssm-ID: 459740 [Multi-domain] Cd Length: 109 Bit Score: 60.69 E-value: 4.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 244 DVDVAPLYGALDRGEQDRAIAPARPGRRKIVLATSIAETSLTIEGVRIVIDsglarvqrFEPDLGLSRLEtvrasrasvd 323
Cdd:pfam00271 38 GIKVARLHGDLSQEEREEILEDFRKGKIDVLVATDVAERGLDLPDVDLVIN--------YDLPWNPASYI---------- 99
|
....*...
gi 658423197 324 QRRGRAGR 331
Cdd:pfam00271 100 QRIGRAGR 107
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
16-164 |
8.79e-10 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 59.43 E-value: 8.79e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 16 AIRAALEASCNLVVVAPPGAGKTTRAPLALLDA-DWAKGGKLILLEPRRLAARAAASRMAATLGEAVGETIGL------R 88
Cdd:smart00487 16 AIEALLSGLRDVILAAPTGSGKTLAALLPALEAlKRGKGGRVLVLVPTRELAEQWAEELKKLGPSLGLKVVGLyggdskR 95
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 658423197 89 MRLESKISARTRIEVVTEGVFARMILDDA-GLEGVAGVLFDEYHERsLDADLGLALAlDAQAGLREDLRLIAMSATL 164
Cdd:smart00487 96 EQLRKLESGKTDILVTTPGRLLDLLENDKlSLSNVDLVILDEAHRL-LDGGFGDQLE-KLLKLLPKNVQLLLLSATP 170
|
|
| HA2 |
pfam04408 |
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in ... |
401-436 |
8.78e-09 |
|
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 461295 [Multi-domain] Cd Length: 104 Bit Score: 53.78 E-value: 8.78e-09
10 20 30
....*....|....*....|....*....|....*..
gi 658423197 401 LGALD-DGRLTDMGRAMRALPLAPRLARMVVEAADHG 436
Cdd:pfam04408 8 LGALDeDGELTPLGRKMAELPLDPRLAKMLLAAAELG 44
|
|
| DEXHc_TDRD9 |
cd17988 |
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also ... |
8-180 |
6.17e-07 |
|
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also known as HIG-1or NET54 or C14orf75) is a part of the nuclear PIWI-interacting RNA (piRNA) pathway essential for transposon silencing and male fertility TDRD9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350746 [Multi-domain] Cd Length: 180 Bit Score: 50.58 E-value: 6.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 8 LPIDDVLPAIRAALEASCNLVVVAPPGAGKTTRAPLALLDaDWAKGGK---LILLEPRRLAARAAASRMAATLGEAVGET 84
Cdd:cd17988 1 LPIYAKREEILSLIEANSVVIIKGATGCGKTTQLPQFILD-HYYKRGKycnIVVTQPRRIAAISIARRVSQEREWTLGSL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 85 IGLRMRLESKISARTRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALALDAQAGLREDLRLIAMSATL 164
Cdd:cd17988 80 VGYQVGLERPASEETRLIYCTTGVLLQKLINNKTLTEYTHIILDEVHERDQELDFLLLVVRRLLRTNSRHVKIILMSATI 159
|
170
....*....|....*.
gi 658423197 165 DGARVAALMGAKTIES 180
Cdd:cd17988 160 SCKEFADYFTTPNNPA 175
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
16-165 |
1.13e-05 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 46.47 E-value: 1.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 16 AIRAALEAScNLVVVAPPGAGKTTRAPLALLDADWAK--GGKLILLEPR-------RLAARAAASRMAATLGEAVGetiG 86
Cdd:pfam00270 7 AIPAILEGR-DVLVQAPTGSGKTLAFLLPALEALDKLdnGPQALVLAPTrelaeqiYEELKKLGKGLGLKVASLLG---G 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 658423197 87 LRMRLESKISARTRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHeRSLDADLGLALALDAQAgLREDLRLIAMSATLD 165
Cdd:pfam00270 83 DSRKEQLEKLKGPDILVGTPGRLLDLLQERKLLKNLKLLVLDEAH-RLLDMGFGPDLEEILRR-LPKKRQILLLSATLP 159
|
|
| DEXHc_Ski2 |
cd17921 |
DEXH-box helicase domain of DEAD-like helicase Ski2 family proteins; Ski2-like RNA helicases ... |
16-171 |
1.48e-05 |
|
DEXH-box helicase domain of DEAD-like helicase Ski2 family proteins; Ski2-like RNA helicases play an important role in RNA degradation, processing, and splicing pathways. They belong to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350679 [Multi-domain] Cd Length: 181 Bit Score: 46.49 E-value: 1.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 16 AIRAALEASCNLVVVAPPGAGKTTRAPLALLDAdWAKGGKLIL----LEPRRLAARAAASRMAATLGEAVGETIGLrMRL 91
Cdd:cd17921 9 ALRALYLSGDSVLVSAPTSSGKTLIAELAILRA-LATSGGKAVyiapTRALVNQKEADLRERFGPLGKNVGLLTGD-PSV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 92 ESKISARTRIEVVTEGVFARMILDDAGLEG--VAGVLFDEYH-----ERSLDADLGLALALDAQaglrEDLRLIAMSATL 164
Cdd:cd17921 87 NKLLLAEADILVATPEKLDLLLRNGGERLIqdVRLVVVDEAHligdgERGVVLELLLSRLLRIN----KNARFVGLSATL 162
|
....*..
gi 658423197 165 DGARVAA 171
Cdd:cd17921 163 PNAEDLA 169
|
|
| BRR2 |
COG1204 |
Replicative superfamily II helicase [Replication, recombination and repair]; |
5-238 |
2.82e-05 |
|
Replicative superfamily II helicase [Replication, recombination and repair];
Pssm-ID: 440817 [Multi-domain] Cd Length: 529 Bit Score: 47.58 E-value: 2.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 5 LSALPIDDVLP----AIRAALEASCNLVVVAPPGAGKTTRAPLALLDAdWAKGGKLILLEPR---RLAARAAASRMAATL 77
Cdd:COG1204 15 LKERGIEELYPpqaeALEAGLLEGKNLVVSAPTASGKTLIAELAILKA-LLNGGKALYIVPLralASEKYREFKRDFEEL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 78 GEAVGETIGLRmRLESKISARTRIEVVTEGVFARMILDDAG-LEGVAGVLFDEYH-----ERSLDADLGLALALDaqagL 151
Cdd:COG1204 94 GIKVGVSTGDY-DSDDEWLGRYDILVATPEKLDSLLRNGPSwLRDVDLVVVDEAHliddeSRGPTLEVLLARLRR----L 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 152 REDLRLIAMSATLDGAR-VAALMGAKTIES--------QGRAFGVETRYlgRDANARIDEAmTRAILLALREERGSILAF 222
Cdd:COG1204 169 NPEAQIVALSATIGNAEeIAEWLDAELVKSdwrpvplnEGVLYDGVLRF--DDGSRRSKDP-TLALALDLLEEGGQVLVF 245
|
250
....*....|....*.
gi 658423197 223 LPGQGEIMRVASRLAE 238
Cdd:COG1204 246 VSSRRDAESLAKKLAD 261
|
|
| PHA02653 |
PHA02653 |
RNA helicase NPH-II; Provisional |
273-342 |
3.09e-04 |
|
RNA helicase NPH-II; Provisional
Pssm-ID: 177443 [Multi-domain] Cd Length: 675 Bit Score: 44.58 E-value: 3.09e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 273 IVLATSIAETSLTIEGVRIVIDSGlaRVQRFEPDLGlsrlETVRASRASVDQRRGRAGRTEPGVCYRLWD 342
Cdd:PHA02653 449 IIISTPYLESSVTIRNATHVYDTG--RVYVPEPFGG----KEMFISKSMRTQRKGRVGRVSPGTYVYFYD 512
|
|
| DEXQc_DQX1 |
cd17986 |
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 ... |
8-174 |
1.73e-03 |
|
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 (DQX1) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350744 [Multi-domain] Cd Length: 177 Bit Score: 40.27 E-value: 1.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 8 LPIDDVLPAIRAALEASCNLVVVA-PPGAGKTTRAPLALLDADWAKG---GKLILLEPRRLAARAAASRMAATLGEAVGE 83
Cdd:cd17986 1 LPIWAAKFTFLEQLESPSGIVLVSgEPGSGKSTQVPQWCAEFALSRGfqkGQVTVTQPHPLAARSLALRVADEMDLNLGH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 84 TIGLRMRLESKISARTRIEVVTEGVFARMILDDAGLEGVAGVLFDEYHERSLDADLGLALALDAQAGlREDLRLIAMSAT 163
Cdd:cd17986 81 EVGYSIPQEDCTGPNTILRFCWDRLLLQEMTSTPLLGAWGVVVLDEAQERSVASDSLLGLLKDVRLQ-RPELRVVVVTSP 159
|
170
....*....|.
gi 658423197 164 LDGARVAALMG 174
Cdd:cd17986 160 ALEPKLRAFWG 170
|
|
| DEXHc_archSki2 |
cd18028 |
DEXH-box helicase domain of archaeal Ski2-type helicase; Archaeal Ski2-type RNA helicases play ... |
16-61 |
4.16e-03 |
|
DEXH-box helicase domain of archaeal Ski2-type helicase; Archaeal Ski2-type RNA helicases play an important role in RNA degradation, processing and splicing pathways. They belong to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350786 [Multi-domain] Cd Length: 177 Bit Score: 39.24 E-value: 4.16e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 658423197 16 AIRAALEASCNLVVVAPPGAGKTTRAPLALLDAdWAKGGKLILLEP 61
Cdd:cd18028 9 AVRAGLLKGENLLISIPTASGKTLIAEMAMVNT-LLEGGKALYLVP 53
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
26-163 |
4.28e-03 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 38.54 E-value: 4.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 658423197 26 NLVVVAPPGAGKTTRAPLALLDADWAKGGKLILLEPrrlaaraaasrmAATLGEAVGETIGLRMRLESKISARTR----- 100
Cdd:cd00046 3 NVLITAPTGSGKTLAALLAALLLLLKKGKKVLVLVP------------TKALALQTAERLRELFGPGIRVAVLVGgssae 70
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 658423197 101 -----------IEVVTEGVFARMILDDAGLEGVAGVL--FDEYHERSLDADLGLALALDAQAGLREDLRLIAMSAT 163
Cdd:cd00046 71 ereknklgdadIIIATPDMLLNLLLREDRLFLKDLKLiiVDEAHALLIDSRGALILDLAVRKAGLKNAQVILLSAT 146
|
|
| SF2_C |
cd18785 |
C-terminal helicase domain of superfamily 2 DEAD/H-box helicases; Superfamily (SF)2 helicases ... |
272-340 |
9.03e-03 |
|
C-terminal helicase domain of superfamily 2 DEAD/H-box helicases; Superfamily (SF)2 helicases include DEAD-box helicases, UvrB, RecG, Ski2, Sucrose Non-Fermenting (SNF) family helicases, and dicer proteins, among others. Similar to SF1 helicases, they do not form toroidal structures like SF3-6 helicases. SF2 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350172 [Multi-domain] Cd Length: 77 Bit Score: 35.76 E-value: 9.03e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 658423197 272 KIVLATSIAETSLTIEGVRIVIdsglarvqrfepdlglsrLETVRASRASVDQRRGRAGR--TEPGVCYRL 340
Cdd:cd18785 24 EILVATNVLGEGIDVPSLDTVI------------------FFDPPSSAASYIQRVGRAGRggKDEGEVILF 76
|
|
| |
