Conserved Protein Domain Family
TRP_2
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pfam08344: TRP_2 (this model, PSSM-Id:285535 is obsolete and has been replaced by 462438)
Transient receptor ion channel II
This domain is found in the transient receptor ion channel (Trp) family of proteins. There is strong evidence that Trp proteins are structural elements of calcium-ion entry channels activated by G protein-coupled receptors. This domain does not tend to appear with the TRP domain (pfam06011) but is often found to the C-terminus of Ankyrin repeats (pfam00023).
Links
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Statistics
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PSSM-Id: 285535
Aligned: 63 rows
Threshold Bit Score: 73.7362
Created: 21-Jul-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q7PTP0       150 CGCDECIRRSSE-DSLRHSLARVNEYRALASPSLIALSSQDPLLTAFQLSWELRNLAFAE 208 Anopheles gambiae str. PEST
XP_009029493 186 CDCEDCKNISER--SLIEALSRQHEYRALASSAYITVSSIDPIIHTFRLYSDLLEESELD 243 Helobdella robusta
ERG85088     219 CLCSECRRIAR---GLSKSVVTLDTYRAISSAAFLWLACSDPSLAAFRLAADLEICMQYE 275 pig roundworm
XP_003143283 153 CSCEECSRSAHC---MTNSVILLDTYRAISSEPFLWLACTDPLLAAFNLATDLQVCEEME 209 eye worm
XP_009029465  46 CTCPEC-EMMED-VSLIEAKTRYTEFKCLASPPYVILSTFDPLLYMFRLNSVLKAESKTE 103 Helobdella robusta
ERG87577     164 CICHKCKRSART---HANGVITLDTYRAISSGPFLWLACADPPLAAFKLALDLEACMQCE 220 pig roundworm
ERG81536     188 CYCEKCADESVR-SS--HAVVKLDTYTAISSDAFLWLACRDPLLAAFKLAADLEVCCQVD 244 pig roundworm
EFA04635     218 CRCMDCKAQLERdDLLHAEHLRLNLYKSVCNPAYICHSSRDPILTSFQLSTELRQCSFLV 277 red flour beetle
EKC33289     165 CNCQECSHKLEF-DELRLAKTRLNAYKGLASCTYISLTSEDPVLTAFDLARELRYVSTIE 223 Pacific oyster
XP_011420072 108 CNCQECSNKLVF-DQLRLAKTRLNAYRGLASSAYISLSSNDPILTAFELARELRCVAKVE 166 Pacific oyster
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